IDENTIFICATION AND GENETICS OF HORSE LYMPHOCYTE ALLOANTIGENS
IDENTIFICATION AND GENETICS OF HORSE LYMPHOCYTE ALLOANTIGENS
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DOI：
10.1007/bf01567818
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发表时间：
1980-01-01
期刊：
影响因子：
3.2
通讯作者：
BAILEY, E
中科院分区：
文献类型：
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作者：
BAILEY, E
用550头经产马的淋巴细胞毒性抗血清和58头用马血细胞同种免疫产生的抗血清检测马[600]。七马淋巴细胞的特异性进行了鉴定，使用相关性分析的测试数据，吸收分析和lysostripping。这些特异性在淋巴细胞和血小板上表达，但不在红细胞（RBC）上表达。这些特异性似乎不是马的8种已知血型系统中任何一种的产物。这些特异性的分布在113纯血马和57阿拉伯马。两种特异性是本文报告的其他2种特异性的亚型。家系研究表明，所有这些特异性都是1个遗传系统的产物。目前尚不清楚该系统是否由1个或多个基因座组成。
Horses [600] were tested with lymphocytotoxic antisera derived from 550 parous mares and 58 antisera produced by alloimmunization with horse blood cells. Seven equine lymphocyte specificities were identified using correlation analysis of the test data, absorption analysis and lysostripping. These specificities are expressed on lymphocytes and platelets, but not on red blood cells (RBC). These specificities do not appear to be products of any of the 8 known blood group systems of the horse. The distribution of these specificities in 113 Thoroughbred horses and 57 Arabian horses is presented. Two specificities are subtypic to 2 other specificities reported here. Family studies indicated that all of these specificities are products of 1 genetic system. It is not clear whether the system consists of 1 or more loci.