PSCA mRNA expression in preoperatively negative prostate biopsies predicts incidental prostate cancer in patients undergoing transurethral resection of the prostate for benign prostatic hyperplasia

PSCA mRNA expression in preoperatively negative prostate biopsies predicts incidental prostate cancer in patients undergoing transurethral resection of the prostate for benign prostatic hyperplasia
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DOI:
10.1002/jso.21996
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发表时间:
2011-11
影响因子:
2.5
通讯作者:
Zhigang Zhao;W. Ma;G. Zeng;D. Qi
Zhigang Zhao;W. Ma;G. Zeng;D. Qi
中科院分区:
医学3区
文献类型:
--
作者:
Zhigang Zhao;W. Ma;G. Zeng;D. Qi

文献摘要

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最近的数据显示,前列腺干细胞抗原(PSCA) mRNA表达可预测前列腺增生患者接受TURP治疗后的癌症。本研究旨在确定术前阴性活检中PSCA mRNA的表达是否能在TURP组织分析中识别偶发性前列腺癌(IPCa)的存在。
Recent data showed that prostate stem cell antigen (PSCA) mRNA expression is predictive of the subsequent cancer in BPH patients treated with TURP. This study was to determine whether PSCA mRNA expression in preoperatively negative biopsies identified the presence of incidental prostate cancer (IPCa) on TURP tissues analysis.