Lithium and clonazepam treatment of two cases with cluster headache
Lithium and clonazepam treatment of two cases with cluster headache
复制标题
锂盐与氯硝西泮治疗丛集性头痛二例
DOI：
10.1046/j.1440-1819.1999.00573.x
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发表时间：
1999
影响因子：
11.9
通讯作者：
S. Yamawaki
中科院分区：
文献类型：
--
作者：
M. Takebayashi;T. Fujikawa;A. Kagaya;J. Horiguchi;S. Yamawaki
丛集性头痛的患者通常使用锂盐治疗。然而，也有一些患者不能完全用锂来治疗。两名丛集性头痛患者接受了氯硝西潘的治疗，氯硝西潘是最有效的苯二氮卓类药物之一。例1锂可延长缓解期，加用氯硝西潘可进一步延长缓解期。例2经氯硝西潘治疗后症状减轻，联合锂治疗6个月后症状缓解。这些发现表明，锂和氯硝西潘的联合治疗可能对丛集性头痛患者有效。
Patients with cluster headache are often treated with lithium. However, there are some patients who can not be fully treated with lithium alone. Two patients with cluster headache were treated with clonazepam, one of the most potent benzodiazepines. Lithium prolonged the period of remission, and the addition of clonazepam further prolonged it in case 1. Treatment with clonazepam reduced the symptoms in case 2, and when combined with lithium, the disorder went into remission after 6 months. These findings suggest that the combination of lithium and clonazepam may be effective in patients with cluster headache.