Prevalence of iron deficiency in the United States
Prevalence of iron deficiency in the United States
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DOI：
10.1001/jama.277.12.973
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发表时间：
1997-03-26
影响因子：
120.7
通讯作者：
Johnson, CL
中科院分区：
文献类型：
--
作者：
Looker, AC;Dallman, PR;Johnson, CL
客观。-为了确定美国人群中缺铁和缺铁性贫血的患病率。具有全国代表性的横断面健康检查调查，包括静脉血铁状态的测量。缺铁，定义为具有异常值至少2 3铁状态的实验室测试（红细胞原卟啉，转铁蛋白饱和度，或血清铁蛋白）;和缺铁性贫血，定义为缺铁加上低血红蛋白。对1988-1994年第三次全国健康与营养调查中24894名1岁及以上儿童进行了调查。9%的1至2岁幼儿和9%至11%的少女和育龄妇女缺铁;其中，缺铁性贫血分别为3%和2%至5%。这些患病率相当于约70万幼儿和780万妇女缺铁;其中约24万幼儿和330万妇女缺铁性贫血。在年龄较大的儿童或50岁以上的儿童中，缺铁率不超过7%，在青少年男孩和年轻男子中，缺铁率不超过1%。在育龄妇女中，铁缺乏症更可能发生在少数民族、低收入和多产的妇女中。缺铁和缺铁性贫血在幼儿、少女和育龄妇女中仍然相对常见。
Objective.-To determine the prevalence of iron deficiency and iron deficiency anemia in the US population.Design.-Nationally representative cross-sectional health examination survey that included venous blood measurements of iron status.Main Outcome Measures.-Iron deficiency, defined as having an abnormal value for at least 2 of 3 laboratory tests of iron status (erythrocyte protoporphyrin, transferrin saturation, or serum ferritin); and iron deficiency anemia, defined as iron deficiency plus low hemoglobin.Participants.-A total of 24 894 persons aged 1 year and older examined in the third National Health and Nutrition Examination Survey (1988-1994).Results.-Nine percent of toddlers aged 1 to 2 years and 9% to 11% of adolescent girls and women of childbearing age were iron deficient; of these, iron deficiency anemia was found in 3% and 2% to 5%, respectively. These prevalences correspond to approximately 700 000 toddlers and 7.8 million women with iron deficiency; of these, approximately 240 000 toddlers and 3.3 million women have iron deficiency anemia. Iron deficiency occurred in no more than 7% of older children or those older than 50 years, and in no more than 1% of teenage boys and young men. Among women of childbearing age, iron deficiency was more likely in those who are minority, low income, and multiparous.Conclusion.-Iron deficiency and iron deficiency anemia are still relatively common in toddlers, adolescent girls, and women of childbearing age.