Retinal detachment in ocular toxoplasmosis

Retinal detachment in ocular toxoplasmosis
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DOI:
10.1016/s0161-6420(99)00013-5
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发表时间:
2000-01-01
期刊:
影响因子:
13.7
通讯作者:
Rothova, A
Rothova, A
中科院分区:
医学1区
文献类型:
--
作者:
Bosch-Driessen, LH;Karimi, S;Rothova, A

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目的:目的:报告眼弓形虫病患者视网膜裂孔和脱离的临床病程和预后。设计:回顾性横断面观察研究。参与者:150例眼弓形虫病患者。干预:回顾1990年至1997年来我科就诊的眼弓形虫病患者的所有记录。主要结果测量:分析视网膜脱离或裂孔的存在以及可能的危险因素,如年龄、近视、最后一次炎症复发与视网膜脱离发作之间的间隔、玻璃体炎的严重程度、既往治疗方法和视网膜异常的位置。我们发现,在我们的眼弓形虫病患者中,视网膜脱离的发生率为6%(9/150),视网膜裂孔的发生率为5%(7/150)。在视网膜脱离或视网膜裂孔之前的活动性眼弓形虫病的发作以严重的眼内炎症为特征。我们的视网膜脱离或视网膜裂孔患者的近视发生率明显高于无视网膜脱离或视网膜裂孔的眼弓形虫病患者。视网膜脱离患者的功能预后差;视网膜脱离导致的法律的盲(视力小于或等于20/200)发生在5的9 patients.Conclusions:仔细的视网膜检查眼弓形虫病是必要的,特别是在近视和严重的眼内炎症患者。眼科学2000; 107:36-40(C)2000,美国眼科学会。
Purpose: To report on the clinical course and prognosis of retinal breaks and detachment occurring in patients with ocular toxoplasmosis.Design: Retrospective cross-sectional observational study.Participants: One hundred fifty consecutive patients with ocular toxoplasmosis.Intervention: A review of all records of patients with ocular toxoplasmosis who had consulted our department from 1990 through 1997 was performed.Main Outcome Measures: The presence of retinal detachment or breaks and possible risk factors, such as age, myopia, the interval between the last recurrence of inflammation and the onset of retinal detachment, severity of vitritis, previous treatment methods, and the location of the retinal abnormalities, were analyzed.Results: We found a frequency of 6% (9/150) for retinal detachment and an additional 5% (7/150) for retinal breaks among our patients with ocular toxoplasmosis. Attacks of active ocular toxoplasmosis preceding the retinal detachment or retinal breaks were characterized by severe intraocular inflammation. The frequency of myopia in our patients with retinal detachment or retinal breaks was significantly higher than in patients with ocular toxoplasmosis without retinal detachment or retinal breaks. The functional prognosis for the patients with retinal detachment was poor; legal blindness (visual acuity less than or equal to 20/200) resulting from retinal detachment occurred in five of the nine patients.Conclusions: Careful retinal examination in ocular toxoplasmosis is warranted, especially in patients with myopia and severe intraocular inflammation. Ophthalmology 2000; 107:36-40 (C) 2000 by the American Academy of Ophthalmology.