The relationship between specific cognitive functions and falls in aging
The relationship between specific cognitive functions and falls in aging
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DOI：
10.1037/0894-4105.21.5.540
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发表时间：
2007-09-01
期刊：
影响因子：
2.4
通讯作者：
Verghese, Joe
中科院分区：
文献类型：
--
作者：
Holtzer, Roee;Friedman, Rachel;Verghese, Joe
本研究调查了不符合痴呆或轻度认知障碍标准的老年人（N = 172）的认知功能和福尔斯之间的关系。为了解决以前研究的局限性，作者通过认知功能和福尔斯之间的关联来控制步态测量和其他风险因素的混杂效应。一个神经心理测试电池提交因素分析，产生3个正交因素（言语智商，速度/执行注意力，记忆）。评价了过去12个月内的单次和复发性福尔斯。作者假设速度/执行注意力与福尔斯有关。此外，作者评估了不同认知功能与福尔斯之间的关联是否因检查的是单一还是复发性福尔斯而异。多变量logistic回归分析显示，速度/执行注意力评分较低与单次和复发性福尔斯风险增加相关。言语智商得分较低仅与复发性福尔斯风险增加相关。记忆力与单次或复发性福尔斯跌倒无关。这些发现与福尔斯的风险评估和预防有关，并指出认知和运动功能可能共有的神经基质。
The current study examined the relationship between cognitive function and falls in older people who did not meet criteria for dementia or mild cognitive impairment (N = 172). To address limitations of previous research, the authors controlled for the confounding effects of gait measures and other risk factors by means of associations between cognitive function and falls. A neuropsychological test battery was submitted to factor analysis, yielding 3 orthogonal factors (Verbal IQ, Speed/Executive Attention, Memory). Single and recurrent falls within the last 12 months were evaluated. The authors hypothesized that Speed/Executive Attention would be associated with falls. Additionally, the authors assessed whether associations between different cognitive functions and falls varied depending on whether single or recurrent falls were examined. Multivariate logistic regressions showed that lower scores on Speed/ Executive Attention were associated with increased risk of single and recurrent falls. Lower scores on Verbal IQ were related only to increased risk of recurrent falls. Memory was not associated with either single or recurrent falls. These findings are relevant to risk assessment and prevention of falls and point to possible shared neural substrates of cognitive and motor function.