Aberrant Oscillatory Activity during Simple Movement in Task-Specific Focal Hand Dystonia.
Aberrant Oscillatory Activity during Simple Movement in Task-Specific Focal Hand Dystonia.
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DOI：
10.3389/fneur.2012.00165
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发表时间：
2012-01-01
影响因子：
3.4
通讯作者：
Nagarajan, Srikantan S
中科院分区：
文献类型：
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作者：
Hinkley, Leighton B N;Dolberg, Rebecca;Nagarajan, Srikantan S
在任务特异性局灶性手肌张力障碍（tspFHD），在运动系统中的皮质活动的时间动力学，以及这些过程是如何相关的感觉和运动功能障碍知之甚少。在这里，我们使用时频重建的脑磁图（MEG）数据来阐述运动过程中皮层活动的时间和空间特征。11例tspFHD患者和11例匹配的健康对照者在MEG记录期间进行了自起搏手指敲击任务。在两组中，在按下按钮期间，在感觉和运动皮层上发现了β（12- 30 Hz）和高γ（65- 90 Hz）振荡活动的强烈变化。大幅下降[p
In task-specific focal hand dystonia (tspFHD), the temporal dynamics of cortical activity in the motor system and how these processes are related to impairments in sensory and motor function are poorly understood. Here, we use time-frequency reconstructions of magnetoencephalographic (MEG) data to elaborate the temporal and spatial characteristics of cortical activity during movement. A self-paced finger tapping task during MEG recording was performed by 11 patients with tspFHD and 11 matched healthy controls. In both groups robust changes in beta (12-30Hz) and high gamma (65-90Hz) oscillatory activity were identified over sensory and motor cortices during button press. A significant decrease [p