Brief intervention for daily marijuana users identified by screening in primary care: A subgroup analysis of the ASPIRE randomized clinical trial.

Brief intervention for daily marijuana users identified by screening in primary care: A subgroup analysis of the ASPIRE randomized clinical trial.
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DOI:
10.1080/08897077.2015.1075932
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发表时间:
2016-04
期刊:
影响因子:
3.5
通讯作者:
Saitz R
Saitz R
中科院分区:
医学3区
文献类型:
--
作者:
Fuster D;Cheng DM;Wang N;Bernstein JA;Palfai TP;Alford DP;Samet JH;Saitz R

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The use of brief intervention for decreasing frequent marijuana use holds potential, but its efficacy in primary care is not known. To assess the impact of two brief interventions on marijuana use among daily/ or almost daily marijuana users. Subgroup analysis of a 3-arm randomized clinical trial of two brief counseling interventions compared to no brief intervention on daily marijuana use in a primary care setting (ASPIRE). ASPIRE study participants who both reported 21–30 days of marijuana use during the past month and identified marijuana as their drug of most concern. 1) Brief Negotiated Interview (BNI), a 10–15 minute structured interview, and 2) an Adaptation of Motivational Interviewing (MOTIV), a 30–45 minute intervention. Control group participants received only a list of substance use treatment resources. The primary outcome was number of days of marijuana use in the past 30 days at the 6-month follow-up. Secondary outcomes were 1) number of days of marijuana use at 6-week follow-up and 2) drug problems (Short Inventory of Problems, SIP-D) at 6-week and 6-month. Differences between intervention groups were analyzed using negative binomial regression models. Among the 167 eligible participants, we did not find any significant impact of either of the two interventions on past 30 days of marijuana use at 6-months [adjusted incidence rate ratio (aIRR): 0.95 (95% confidence interval (CI)):0.75–1.15, p=0.82 for BNI vs. control; aIRR:1.02, 95%CI:0.85–1.23, p=0.82 for MOTIV vs. control]. There was no significant impact on drug-related problems at 6-month follow-up [aIRR:1.12 (95%CI:0.69–1.82) p=0.66 and aIRR:1.46 (95%CI:0.89–2.38) p=0.27 for BNI vs. control and MOTIV vs. control, respectively]. Results were similar at 6 weeks. Brief intervention has no apparent impact on marijuana use or drug-related problems among primary care patients with frequent marijuana use identified by screening.