Quality of life in long-term survivors of cervical cancer
Quality of life in long-term survivors of cervical cancer
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DOI：
10.1016/s0378-5122(99)00020-1
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发表时间：
1999-06-21
期刊：
影响因子：
4.9
通讯作者：
Iosif, C
中科院分区：
文献类型：
--
作者：
Li, CR;Samsioe, G;Iosif, C
目的：本研究的目的是评估宫颈癌幸存者样本的生活质量。研究设计：在这项研究中，评估了46名临床I期或II期宫颈癌幸存者和1名0期幸存者。从一项正在进行的队列研究中选择两个对照组，其中527名妇女绝经后，344名妇女绝经后HRT。所有对照组和癌症幸存者完成了一份关于个人状况、医疗监督、个人福祉和生活质量的自我评估问卷。结果：18例宫颈癌患者保留卵巢。共有28名幸存者，谁有卵巢切除术，与对照组进行了比较。大多数癌症幸存者有良好的社会经济背景和积极的生活方式。42%的人目前正在接受医疗监督，并定期使用药物。卵巢切除术组HRT使用者的比例较高（短期和长期治疗均为36%）。在生活质量方面，卵巢切除术后存活者和对照组之间没有显著差异。保留卵巢组除心理状况较差外，其余生活质量指标与切除卵巢组相近。结论：宫颈癌长期生存者的生活质量总体上是令人满意的。积极的结果可能是由于HRT使用率较高，卵巢保存，良好的教育，工作条件以及积极的生活方式。(C)1999爱思唯尔科学爱尔兰有限公司保留所有权利。
Objective: The aim of this study was to evaluate the quality of life within a sample of cervical cancer survivors. Study design: In this study, 46 cervical cancer survivors at clinical stage I or II and one survivor at stage 0, were evaluated. Two control groups were selected from an ongoing cohort study, in which 527 women were postmenopausal and 344 women were postmenopausal with HRT. All controls and cancer survivors completed a self-evaluating questionnaire pertaining to personal conditions, medical surveillance, individual well-being and quality of life. Results: Eighteen cervical cancer survivors were ovaries preserved. A total of 28 survivors, who had an oophorectomy, were compared with the controls. Most of the cancer survivors had a good socio economic background and an active lifestyle. Forty-two percent were currently under medical surveillance and used medication regularly. The ratio of HRT users was higher in the oophorectomy group (36% in both short- and long-term therapy). With regard to the quality of life, there were no remarkable differences between oophorectomy survivors and controls. Except that the psychological condition in the ovaries preserved group was worse, the rest of the findings concerning the quality of life derived from the ovaries preserved group were rather close to that of the oophorectomy group. Conclusion: The quality of life in long-term cervical cancer survivors is generally satisfactory. The positive results may be due to the higher ratio of HRT use, ovarian preservation, good education, working conditions, as well as an active lifestyle. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.