Automated lung nodule detection at low-dose CT: preliminary experience.
Automated lung nodule detection at low-dose CT: preliminary experience.
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DOI：
10.3348/kjr.2003.4.4.211
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发表时间：
2003-10
影响因子：
4.8
通讯作者：
Im JG
中科院分区：
文献类型：
--
作者：
Goo JM;Lee JW;Lee HJ;Kim S;Kim JH;Im JG
确定计算机辅助诊断（CAD）系统在低剂量CT自动检测肺结节中的有效性。一个用于检测肺结节的CAD系统被用来处理由50个连续的低剂量CT扫描提供的数据。将初始报告的结果、两名胸部放射科医生的第二次检查结果与CAD系统获得的结果进行比较，通过审查所有这些结果，建立了金标准。通过应用金标准，共确定了52个结节（26个直径≤ 5 mm; 26个直径> 5 mm）。与最初的报告相比，CAD系统又发现了四个结核。其中三个，只在CAD确定，形成了用于推导金本位的数据的一部分。对于直径> 5 mm的结节的检测，初始报告的灵敏度为77%，第二次检查的灵敏度为88%，CAD系统的灵敏度为65%。每项CT研究有8.0±5.2个假阳性CAD结果。这些初步结果表明，CAD系统可以提高低剂量CT肺结节的检测。
To determine the usefulness of a computer-aided diagnosis (CAD) system for the automated detection of lung nodules at low-dose CT. A CAD system developed for detecting lung nodules was used to process the data provided by 50 consecutive low-dose CT scans. The results of an initial report, a second look review by two chest radiologists, and those obtained by the CAD system were compared, and by reviewing all of these, a gold standard was established. By applying the gold standard, a total of 52 nodules were identified (26 with a diameter ≤ 5 mm; 26 with a diameter > 5 mm). Compared to an initial report, four additional nodules were detected by the CAD system. Three of these, identified only at CAD, formed part of the data used to derive the gold standard. For the detection of nodules > 5 mm in diameter, sensitivity was 77% for the initial report, 88% for the second look review, and 65% for the CAD system. There were 8.0±5.2 false-positive CAD results per CT study. These preliminary results indicate that a CAD system may improve the detection of pulmonary nodules at low-dose CT.