Computerized image analysis for quantitative measurement of vessel diameter from cineangiograms.
Computerized image analysis for quantitative measurement of vessel diameter from cineangiograms.
复制标题
计算机图像分析用于从电影血管照片中定量测量血管直径。
作者：
J. Spears;T. Sandor;A. Als;M. Malagold;J. Markis;W. Grossman;J. Serur;S. Paulin
冠状动脉狭窄血管造影严重程度的主观估计显示出变异性和不准确性。因此，我们测试了一个新开发的计算机图像分析系统的准确性，从电影血管造影定量血管直径。14个已知直径的圆柱形体模填充造影剂，并在广泛的临床相关的放射学条件下拍摄，以开发回归方程，相关的计算机衍生的解剖直径。血管直径的计算机测量值不受血管尺寸、放大率、焦点尺寸、散射介质厚度、千伏峰值或放射学视野内位置的影响，但校正因子对于造影剂浓度的小但显著（p <0.01）线性依赖性是必要的。除快速血管运动和造影剂浓度为50%或更低的泛影葡胺（Renografin 76）外，所有条件下计算机化血管直径测量的准确度范围在+/- 59和+/- 137 mu之间，这两种情况均导致准确度降低以及无法定位直径小于1 mm的血管的管腔边缘。
Subjective estimates of the angiographic severity of coronary artery stenoses show variability and inaccuracy. We therefore tested the accuracy of a newly developed computerized image analysis system for quantitating vessel diameter from cineangiograms. Fourteen cylindrical phantoms of known diameter were filled with contrast medium and filmed over a wide range of clinically relevant radiographic conditions in order to develop regression equations that related computer-derived to anatomic diameters. Computer measurements of vessel diameter were unaffected by vessel size, magnification, focal spot size, thickness of scattering medium, kilovolt peak, or location within the radiographic field, but a correction factor was necessary for a small but significant (p less than .01) linear dependence on contrast medium concentration. The accuracy of computerized vessel diameter measurements ranged between +/- 59 and +/- 137 mu for all conditions except for rapid vessel motion and contrast medium concentrations of 50% or less meglumine diatrizoate (Renografin 76), both of which resulted in reduced accuracy as well as in the inability to locate lumen edges of vessels less than 1 mm in diameter.