Auditory and visual connectivity gradients in frontoparietal cortex.
Auditory and visual connectivity gradients in frontoparietal cortex.
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DOI：
10.1002/hbm.23358
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发表时间：
2017-01
影响因子：
4.8
通讯作者：
Leech R
中科院分区：
文献类型：
--
作者：
Braga RM;Hellyer PJ;Wise RJ;Leech R
大脑区域的额顶叶网络通常涉及听觉和视觉信息处理。虽然这是可能的，同一套多模式的地区subserves两种方式，有越来越多的证据表明，有一个分化的感觉功能内额顶叶皮层。人类的磁共振成像（MRI）被用来研究不同的额顶叶区域是否在与视觉或听觉模式的连接中表现出内在的偏见。用弥散纤维束成像评估结构连接，用功能MRI测试功能连接。观察到功能的背腹梯度，其中与视觉皮层的连接占主导地位的背额叶和顶叶连接，而与听觉皮层的连接占主导地位的腹侧额叶和顶叶区域。梯度也观察到沿着后-前轴，虽然在相反的方向在前额叶和顶叶皮质。结果表明，额顶叶皮层内的神经活动的位置可能会受到这些对视觉和听觉处理的内在偏见。因此，额顶叶皮层的活动位置可能会受到刺激方式的影响，就像任务的认知需求一样。得出的结论是，刺激模态在整个额叶和顶叶皮层中进行空间编码，并推测这种安排允许在高阶皮层内发生模态特定信息的自上而下调制。这可能提供一个潜在的更快，更有效的途径，通过限制额叶和顶叶区域内的调制，而不是与感觉皮层的长距离连接，可以在感觉模态之间进行自上而下的选择。《脑地图》38：255-270，2017年。© 2016 Wiley Periodicals，Inc.
A frontoparietal network of brain regions is often implicated in both auditory and visual information processing. Although it is possible that the same set of multimodal regions subserves both modalities, there is increasing evidence that there is a differentiation of sensory function within frontoparietal cortex. Magnetic resonance imaging (MRI) in humans was used to investigate whether different frontoparietal regions showed intrinsic biases in connectivity with visual or auditory modalities. Structural connectivity was assessed with diffusion tractography and functional connectivity was tested using functional MRI. A dorsal–ventral gradient of function was observed, where connectivity with visual cortex dominates dorsal frontal and parietal connections, while connectivity with auditory cortex dominates ventral frontal and parietal regions. A gradient was also observed along the posterior–anterior axis, although in opposite directions in prefrontal and parietal cortices. The results suggest that the location of neural activity within frontoparietal cortex may be influenced by these intrinsic biases toward visual and auditory processing. Thus, the location of activity in frontoparietal cortex may be influenced as much by stimulus modality as the cognitive demands of a task. It was concluded that stimulus modality was spatially encoded throughout frontal and parietal cortices, and was speculated that such an arrangement allows for top–down modulation of modality‐specific information to occur within higher‐order cortex. This could provide a potentially faster and more efficient pathway by which top–down selection between sensory modalities could occur, by constraining modulations to within frontal and parietal regions, rather than long‐range connections to sensory cortices. Hum Brain Mapp 38:255–270, 2017. © 2016 Wiley Periodicals, Inc.