Attention-deficit hyperactivity disorder symptoms in a clinic sample of children and adolescents with pervasive developmental disorders

Attention-deficit hyperactivity disorder symptoms in a clinic sample of children and adolescents with pervasive developmental disorders
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DOI:
10.1089/cap.2006.16.737
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发表时间:
2006-12-01
影响因子:
1.9
通讯作者:
Ousley, Opal Y.
Ousley, Opal Y.
中科院分区:
医学3区
文献类型:
--
作者:
Lee, Douglas O.;Ousley, Opal Y.

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目的:本系统性病历回顾的目的是确定患有自闭症谱系障碍(ASD)的儿童和青少年的临床样本中注意力缺陷/多动障碍(ADHD)的频率,比较患有自闭症障碍、自闭症障碍和未另行说明的广泛性发育障碍(PDD-NOS)的儿童的ADHD症状,比较患有和不患有ADHD相关主诉的个体的ADHD症状,并确定ADHD评定量表(ADHD RS)评分与年龄之间的相关性。方法:本系统性图表回顾检查了连续被转介到大学自闭症精神药理学项目的儿童和青少年的数据。所有个体均通过半结构化访谈进行ASD和ADHD诊断,ADHD症状使用ADHD RS scores.Results进行评估:在83名儿童中,78%符合精神疾病诊断和统计手册第4版(DSM-IV)ADHD标准,并超过ADHD RS的第93百分位数。自闭症患者的多动-冲动性得分显著高于其他ASD患者。DSM-IV ADHD诊断在患有和不患有ADHD的个体中同样代表他们的主要主诉。ADHD RS、多动性、冲动性和总分与年龄呈负相关。结论:ADHD症状在ASD儿童和青少年中普遍存在。
Objectives: The aims of this systematic chart review were to determine the frequency of attention-deficit/hyperactivity disorder (ADHD) in a clinic sample of children and adolescents with autism spectrum disorders (ASD), to compare ADHD symptoms in children with Autistic Disorder, Asperger's Disorder, and pervasive developmental disorders-not otherwise specified (PDD-NOS), to compare ADHD symptoms in individuals with and without ADHD-related chief complaints, and to determine the correlation between ADHD Rating Scale (ADHD RS) scores and age.Method: This systematic chart review examined data from children and adolescents who were consecutively referred to a university-based autism psychopharmacology program. All individuals were diagnosed by semistructured interview for ASD and ADHD, and ADHD symptoms were assessed using ADHD RS scores.Results: Of 83 children, 78% fulfilled Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) criteria for ADHD and exceeded the 93(rd) percentile norm for the ADHD RS. Hyperactivity-impulsivity scores were significantly greater in individuals with autism than those with other ASDs. DSM-IV ADHD diagnosis was represented equally in individuals with and without ADHD as their chief complaints. ADHD RS hyperactivityimpulsivity and total scores were negatively correlated with age.Conclusion: ADHD symptoms are pervasive in clinically referred children and adolescents with ASD.