Granulomatous interstitial nephritis associated with silica.
Granulomatous interstitial nephritis associated with silica.
复制标题
与二氧化硅相关的肉芽肿性间质性肾炎。
DOI：
10.1111/nep.13006
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发表时间：
2018
期刊：
影响因子：
2.5
通讯作者：
Takeshi Nakata
中科院分区：
文献类型：
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作者：
Iwao M;Suzuki Y;Tanaka R;Koyama T;Ozaki E;Nakata T;Aoki K;Fukuda A;Sato Y;Kuriyama N;Fukunaga N;Sato F;Katagiri F;Ohno K;Shibata H;Mimata H;Itoh H.;迫田雅彦，飯野 聡，橋口真征，佐竹霜一，川崎洋太，蔵原 弘，又木雄弘，前村公成，新地洋之，上野真一，夏越祥次;Masahiko Sakoda，Satoshi Iino，Yota Kawasaki，Motoyuki Hashiguchi，Yuko Mataki，Hiroshi Kurahara，Kosei Maemura，Hiroyuki Shinchi，Shinichi Ueno，Shoji Natsugoe;迫田雅彦，飯野 聡，又木雄弘，橋口真征，川崎洋太，蔵原 弘，前村公成，新地洋之，上野真一，夏越祥次;迫田雅彦，飯野 聡，又木雄弘，南 幸次，川崎洋太，橋口真征，濱田由紀，蔵原 弘，前村公成，新地洋之，上野真一，夏越祥次;Takeshi Nakata
本文介绍一例25岁女性患者，因血肌酐轻微升高而转诊至医院，无蛋白尿和血尿。检查发现尿β-2微球蛋白水平升高，并行肾活检。电子显微镜-金属分析显示溶酶体含有二氧化硅的峰，诊断为与二氧化硅相关的肉芽肿性间质性肾炎。
The article presents a case study of a 25-year-old woman who was referred to a hospital due to slightly elevated serum creatinine without proteinuria and haematuria. Examination revealed higher level of urinary β2microglobulin, and renal biopsy was conducted. Electron microscopy-metal analysis indicated that the lysosomes include peaks of silica, and granulomatous interstitial nephritis associated with silica was diagnosed.