Repetitive transcranial magnetic stimulation for stroke rehabilitation: insights into the molecular and cellular mechanisms of neuroinflammation.
Repetitive transcranial magnetic stimulation for stroke rehabilitation: insights into the molecular and cellular mechanisms of neuroinflammation.
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重复的经颅磁刺激用于中风康复：对神经炎症的分子和细胞机制的洞察。
DOI：
10.3389/fimmu.2023.1197422
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发表时间：
2023
影响因子：
7.3
通讯作者：
中科院分区：
文献类型：
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作者：
卒中是世界范围内导致死亡和残疾的主要原因，大多数幸存者报告了运动、感觉、吞咽、认知、情感和语言等功能障碍。重复经颅磁刺激(RTMS)是一种非侵入性脑刺激(NIBS)技术，能够调节大脑区域的神经兴奋性，已被用于神经和精神疾病。此外，大量研究表明，rTMS对中风患者的功能恢复具有积极的作用。在这篇综述中，我们将总结rTMS在卒中康复中的临床益处，包括改善运动障碍、吞咽困难、抑郁、认知功能和中枢性卒中后疼痛。此外，本综述还将讨论rTMS介导的卒中康复的分子和细胞机制，特别是免疫调节机制，如免疫细胞和炎性细胞因子的调节。此外，还讨论了神经影像技术作为rTMS介导的卒中康复的重要工具，以更好地了解rTMS作用的潜在机制。最后，还阐述了rTMS介导的卒中康复目前面临的挑战和未来的前景，以期加速其在临床上的广泛应用。
Stroke is a leading cause of mortality and disability worldwide, with most survivors reporting dysfunctions of motor, sensation, deglutition, cognition, emotion, and speech, etc. Repetitive transcranial magnetic stimulation (rTMS), one of noninvasive brain stimulation (NIBS) techniques, is able to modulate neural excitability of brain regions and has been utilized in neurological and psychiatric diseases. Moreover, a large number of studies have shown that the rTMS presents positive effects on function recovery of stroke patients. In this review, we would like to summarized the clinical benefits of rTMS for stroke rehabilitation, including improvements of motor impairment, dysphagia, depression, cognitive function, and central post-stroke pain. In addition, this review will also discuss the molecular and cellular mechanisms underlying rTMS-mediated stroke rehabilitation, especially immune regulatory mechanisms, such as regulation of immune cells and inflammatory cytokines. Moreover, the neuroimaging technique as an important tool in rTMS-mediated stroke rehabilitation has been discussed, to better understanding the mechanisms underlying the effects of rTMS. Finally, the current challenges and future prospects of rTMS-mediated stroke rehabilitation are also elucidated with the intention to accelerate its widespread clinical application.
重复的经颅磁刺激对中风患者平衡功能的影响。
DOI：
10.5535/arm.2016.40.5.826
发表时间：
2016-10
期刊：
Annals of rehabilitation medicine
影响因子：
--
作者：
Choi CM;Kim JH;Lee JK;Lee BY;Kee HS;Jung KI;Yoon SR
通讯作者：
Yoon SR