The treatment of delirium tremens and of incomplete alcoholic delirium ‐ a brief history

The treatment of delirium tremens and of incomplete alcoholic delirium ‐ a brief history
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震颤性谵妄和不完全性酒精性谵妄的治疗——简史

DOI:
10.1111/j.1600-0447.1986.tb10550.x
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发表时间:
1986
影响因子:
6.7
通讯作者:
T. Becker
T. Becker
中科院分区:
医学1区
文献类型:
--
作者:
G. Huffmann;T. Becker

文献摘要

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在使用氯甲噻唑治疗谵妄后,死亡率显著下降。大多数统计数据中的死亡率范围为1 - 4%。患者的年龄和各种内脏器官的并发症影响临床结果,氯甲噻唑治疗开始的时间也是如此。然而,这已经引起了在对谵妄早期阶段的轻微怀疑时开氯甲噻唑的习惯。在某些情况下,使用这种药物无疑是不必要的,但同样肯定的是,这种措施往往防止了完全谵妄的发展,现在这种情况比20年前要少见得多。
Followinng the introduction of chlormethiazole for the treatment of delirium tremens a striking reduction in the death rate occurred. The mortality range in most statistics is 1‐4%. The patient's age and complications concerning various internal organs affect the clinical outcome and so does the time at which chlormethiazole treatment is initiated. However, this has given rise to the habit of prescribing chlormethiazole at the slightest suspicion of the early stages of delirium tremens. In some cases the use of the drug was no doubt unnecessary, but equally certainly this measure has often prevented the development of complete delirium tremens which is now seen far more rarely than it was 20 years ago.