Response of primary hepatic amyloidosis to melphalan and prednisone: a case report and review of the literature.
Response of primary hepatic amyloidosis to melphalan and prednisone: a case report and review of the literature.
复制标题
原发性肝淀粉样变性对马法兰和泼尼松的反应：病例报告和文献综述。
DOI：
10.1016/s0025-6196(12)61853-9
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发表时间：
1986
影响因子：
8.9
通讯作者：
Kyle,RA
中科院分区：
文献类型：
--
作者：
Gertz,MA;Kyle,RA
我们报告了第一例经活检证实的原发性肝淀粉样变性，在用马法兰和泼尼松治疗后组织学消退。根据已报道的治疗这种罕见浆细胞营养不良的累积经验，我们建议对原发性肝淀粉样变性患者进行细胞毒治疗的试验。
We report the first case of biopsy-proven primary hepatic amyloidosis in which histologic regression was demonstrated after therapy with melphalan and prednisone. On the basis of the cumulative reported experience regarding the treatment of this rare plasma cell dyscrasia, we recommend a trial of cytotoxic therapy for patients with primary hepatic amyloidosis.