Epidemiologic impact of children with brain tumors
Epidemiologic impact of children with brain tumors
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DOI：
10.1007/s003810050467
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发表时间：
1999-11-01
影响因子：
1.4
通讯作者：
Bleyer, WA
中科院分区：
文献类型：
--
作者：
Bleyer, WA
中枢神经系统肿瘤在儿童和青少年时期的影响一直在稳步增加。在许多国家，脑和脊髓肿瘤的发病率目前仅次于白血病，是影响儿童的癌症，也是年轻人癌症死亡的最常见原因。在美国，脑肿瘤现在比急性淋巴细胞白血病更常见，并且中枢神经系统肿瘤导致的癌症死亡比例在过去 25 年中几乎翻了一番。全球每年约有 30,000-40,000 名儿童罹患中枢神经系统肿瘤，其中大多数无法存活。与儿童期发生的大多数其他恶性肿瘤相比，中枢神经系统肿瘤的治疗效果尚未取得可比的成功，而且尚未确定特定的危险因素或一组危险因素来解释相当大比例的中枢神经系统肿瘤的发生。在许多国家，中枢神经系统肿瘤现在是儿科肿瘤学面临的最大挑战。
The impact of CNS tumors during childhood and adolescence has been steadily increasing. In many countries, brain and spinal cord tumors are now second in frequency only to leukemia as a cancer affecting children, and the most common cause of cancer mortality in the young. In the United States, brain tumors are now more common than acute lymphoblastic leukemia, and the proportion of cancer deaths due to CNS tumors has nearly doubled during the past 25 years. Worldwide, approximately 30,000-40,000 children develop CNS tumors each year, and the majority do not survive. Compared with most other malignancies that occur during childhood, CNS tumors have not been treated with comparable success in treatment outcome, also, no specific risk factor, or set of risk factors, has been identified to explain a substantial proportion of CNS tumor occurrence. In many countries, CNS tumors are now the greatest challenge in pediatric oncology.