Current US Guidelines for Prescribing HIV Pre-exposure Prophylaxis (PrEP) Disqualify Many Women Who Are at Risk and Motivated to Use PrEP
Current US Guidelines for Prescribing HIV Pre-exposure Prophylaxis (PrEP) Disqualify Many Women Who Are at Risk and Motivated to Use PrEP
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DOI：
10.1097/qai.0000000000002042
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发表时间：
2019-08-01
影响因子：
3.6
通讯作者：
Kershaw, Trace S.
中科院分区：
文献类型：
--
作者：
Calabrese, Sarah K.;Willie, Tiara C.;Kershaw, Trace S.
背景：美国疾病控制和预防中心的 HIV 暴露前预防 (PrEP) 临床指南被广泛用于评估患者的 PrEP 资格。该指南包括两个版本的标准——指导概要标准和推荐适应症标准——对于异性恋活跃女性来说，这两个版本存在潜在的关键差异：两者都要求女性了解自己的危险行为，但推荐适应症也要求女性了解其伴侣的艾滋病毒风险或认识到潜在的无症状性传播感染。本研究根据这两种不同版本的风险和动机类别标准检查了女性的 PrEP 资格。背景/方法：2017 年对最近在康涅狄格州计划生育中心从事护理的 HIV 阴性女性 (n = 679) 进行了在线调查。该调查根据疾病控制和预防中心的两个版本标准、HIV 风险指标、PrEP 动机指标和社会人口统计学评估了 PrEP 资格。 结果：参与者大多是非西班牙裔白人 (33.9%) 或黑人 (35.8%)，收入较低（
Background: US Centers for Disease Control and Prevention clinical guidelines for HIV pre-exposure prophylaxis (PrEP) are widely used to assess patients' PrEP eligibility. The guidelines include 2 versions of criteria-guidance summary criteria and recommended indications criteria-that diverge in a potentially critical way for heterosexually active women: Both require women's knowledge of their own risk behavior, but the recommended indications also require women's knowledge of their partners' HIV risk or recognition of a potentially asymptomatic sexually transmitted infection. This study examined women's PrEP eligibility according to these 2 different versions of criteria across risk and motivation categories.Setting/Methods: HIV-negative women (n = 679) recently engaged in care at Connecticut Planned Parenthood centers were surveyed online in 2017. The survey assessed PrEP eligibility by both versions of Centers for Disease Control and Prevention criteria, HIV risk indicators, PrEP motivation indicators, and sociodemographic characteristics.Results: Participants were mostly non-Hispanic white (33.9%) or black (35.8%) and had low income (