HIGHLY OXYGENATED QUASSINOIDS FROM EURYCOMA-LONGIFOLIA
HIGHLY OXYGENATED QUASSINOIDS FROM EURYCOMA-LONGIFOLIA
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DOI：
10.1016/0031-9422(93)85475-7
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发表时间：
1993-06-01
期刊：
影响因子：
3.8
通讯作者：
IITAKA, Y
中科院分区：
文献类型：
--
作者：
MORITA, H;KISHI, E;IITAKA, Y
从东革阿里的叶子中分离出两种新型 C19 骨架苦木素，一种在 C-7 处具有内酯键，另一种在 C-12 处具有内酯键，以及七种具有 C20 骨架的新型高氧苦木素。它们的结构和立体化学是通过光谱数据确定的，包括二维核磁共振技术和 X 射线分析。还讨论了它们的结构和细胞毒性之间的关系。
Two novel C19-skeleton quassinoids, one with a lactonic linkage at C-7 and another with a lactonic linkage at C-12, and seven novel highly oxygenated quassinoids with a C20-skeleton were isolated from the leaves of Eurycoma longifolia. Their structures and stereochemistry were established by spectroscopic data, including two-dimensional NMR techniques, and X-ray analysis. The relationships between their structures and cytotoxicities are also discussed.