Yellow fever: Epidemiology and prevention

Yellow fever: Epidemiology and prevention
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DOI:
10.1086/511869
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发表时间:
2007-03-15
影响因子:
11.8
通讯作者:
Barnett, Elizabeth D.
Barnett, Elizabeth D.
中科院分区:
医学1区
文献类型:
--
作者:
Barnett, Elizabeth D.

文献摘要

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黄热病继续在非洲和南美洲地区发生,尽管有有效的疫苗可用。最近,一些接受黄热病疫苗接种的人被描述为患有严重的神经系统疾病和多器官系统疾病。这些事件将注意力集中在需要确定合理使用黄热病疫苗的标准,并描述可能与黄热病疫苗有关的不良事件的范围。描述将增加这些事件风险的宿主因素并确定黄热病和黄热病疫苗相关不良事件的潜在治疗方式是密集调查的主题。
Yellow fever continues to occur in regions of Africa and South America, despite the availability of effective vaccines. Recently, some cases of severe neurologic disease and multiorgan system disease have been described in individuals who received yellow fever vaccine. These events have focused attention on the need to define criteria for judicious use of yellow fever vaccine and to describe the spectrum of adverse events that may be associated with yellow fever vaccine. Describing host factors that would increase risk of these events and identifying potential treatment modalities for yellow fever and yellow fever vaccine associated adverse events are subjects of intense investigation.