Lignan and isoflavonoid concentrations in tea and coffee.
Lignan and isoflavonoid concentrations in tea and coffee.
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茶和咖啡中的木脂素和异黄酮浓度。
DOI：
10.1079/bjn19980007
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发表时间：
1998
期刊：
影响因子：
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通讯作者：
Adlercreutz,H
中科院分区：
文献类型：
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作者：
Mazur,WM;Wähälä,K;Rasku,S;Salakka,A;Hase,T;Adlercreutz,H
茶是世界各地广泛消费的饮料。据报道，茶叶中存在具有抗突变、抗癌和抗氧化特性的化学预防化合物。最近研究表明，大量摄入茶和含有类黄酮的食物与冠心病的发生呈负相关。然而，茶可能含有具有类似活性的其他化合物。使用新的气相色谱-质谱法，我们测量了 20 种商业茶（红茶、绿茶和红茶品种）样品中的木酚素和异黄酮类化合物，以及作为比较的六种咖啡。对未冲泡的茶和冲泡的茶进行了研究。对茶叶的分析发现，木酚素开环异落叶松树脂醇（5.6-28.9 mg/kg；15.9-81.9 μmol/kg）和马泰尔树脂醇（0.56-4.13 mg/kg；1.6-11.5 μmol/kg）含量相对较高，但异黄酮类化合物含量较低。由于植物木脂素及其哺乳动物代谢物肠内酯和肠二醇具有抗氧化特性，并且这些哺乳动物木脂素在血浆中浓度很高，因此我们推测木脂素多酚可能有助于茶对冠心病的保护作用。
Tea is a beverage consumed widely throughout the world. The existence in tea of chemopreventing compounds possessing antimutagenic, anticarcinogenic and antioxidative properties has been reported. High intakes of tea and foods containing flavonoids have recently been shown to be negatively correlated to the occurrence of CHD. However, tea may contain other compounds with similar activities. Using a new gas chromatographic–mass spectrometric method we measured lignans and isoflavonoids in samples of twenty commercial teas (black, green and red varieties) and, for comparison, six coffees. Both unbrewed and brewed tea were investigated. The analysis of the teas yielded relatively high levels of the lignans secoisolariciresinol (5.6–28.9 mg/kg; 15.9–81.9 μmol/kg) and matairesinol (0.56–4.13 mg/kg; 1.6–11.5 μmol/kg) but only low levels of isoflavonoids. Because the plant lignans, as well as their mammalian metabolites enterolactone and enterodiol, have antioxidative properties and these mammalian lignans occur in high concentrations in plasma, we hypothesize that lignan polyphenols may contribute to the protective effect of tea on CHD.