Comparing the psychometric properties of the EQ-5D-3L and EQ-5D-5L in cancer patients in Korea
Comparing the psychometric properties of the EQ-5D-3L and EQ-5D-5L in cancer patients in Korea
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DOI：
10.1007/s11136-011-0018-1
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发表时间：
2012-08-01
影响因子：
3.5
通讯作者：
Jo, Min-Woo
中科院分区：
文献类型：
--
作者：
Kim, Seon Ha;Kim, Hwa Jung;Jo, Min-Woo
目的比较EQ-5D-3L和EQ-5D-3L在韩国癌症患者中的效度、信息量和信度。分析了EQ-5D-3L和EQ-5D-5L在各维度上的再分布特性。信息性评价采用香农信息熵和天花板效应。通过比较EQ-VAS、ECOG表现状态和EORTC QLQ-C30子量表来评价收敛效度。结果EQ-5D-3L的所有水平基本上被划分为EQ-5D-5L的相关水平。两个版本的平均不符合率为3.5%。EQ-5D-5L的绝对信息量高于EQ-5D-3L，但两者的信息效率趋于相似。完全健康的比例(11111)从EQ-5D-3L的16.8%下降到EQ-5D-5L的9.7%。EQ-5D-5L与EQ-VAS、ECOG表现状态和EORTC QLQ-C30的相关性与EQ-5D-3L相似或更高。EQ-5D-5L指数的组内相关系数为0.77。结论EQ-5D-5L比EQ-5D-3L具有更大的信息量和更低的天花板效应发生率。EQ-5D-5L具有较好的结构效度和较好的信度。因此，考虑到这些发现，EQ-5D-5L可能比EQ-5D-3L更可取。
Purpose This study was conducted to assess the redistribution properties of the EQ-5D-3L when using the EQ-5D-5L and to compare the validity, informativity, and reliability of both EQ-5D-3L and EQ-5D-5L in Korean cancer patients.Methods Patients visiting one ambulatory cancer center self-administered the two versions of the EQ-5D and the EORTC QLQ-C30 questionnaire. Redistribution properties in each dimension of EQ-5D were analyzed between EQ-5D-3L and EQ-5D-5L. Informativity was evaluated using the Shannon entropy and ceiling effect. Convergent validity was evaluated by comparing the EQ-VAS, ECOG performance status, and EORTC QLQ-C30 subscales. Reliability was also evaluated in terms of test-retest reliability.Results All levels of the EQ-5D-3L substantially partitioned into associated levels of the EQ-5D-5L. The average inconsistency rate of the two versions was 3.5%. Absolute informativity was higher for the EQ-5D-5L than for the EQ-5D-3L, but their informative efficiency tended to be similar. The proportion of 'perfect health' (11111) decreased from 16.8% in the EQ-5D-3L to 9.7% in the EQ-5D-5L. EQ-5D-5L demonstrated similar or higher correlations with the EQ-VAS, ECOG performance status, and EORTC QLQ-C30, than the EQ-5D-3L. The intra-class correlation coefficient of the EQ-5D-5L index was 0.77.Conclusions The EQ-5D-5L had greater informativity and lower rate in the ceiling effect than those values of the EQ-5D-3L. The EQ-5D-5L showed good construct validity and reasonable reliability. Therefore, considering these findings, the EQ-5D-5L may be preferable to the EQ-5D-3L.