Necrotizing enterocolitis.

Necrotizing enterocolitis.
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坏死性小肠结肠炎。

DOI:
10.1007/bf02762112
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发表时间:
2001-09
影响因子:
4.3
通讯作者:
Vigneswaran R
Vigneswaran R
中科院分区:
医学4区
文献类型:
--
作者:
Kulkarni A;Vigneswaran R

文献摘要

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低出生体重儿存活率的提高,特别是在印度的新生儿重症监护病房,似乎伴随着早期幸存者中的坏死性小肠结肠炎(NEC)的频繁识别。随着对幼儿的先进护理的理念和实践在该国变得更加可接受和负担得起,可以预见这类婴儿的存活率将稳步上升。然而,印度越来越担心NEC可能成为未来发病率和死亡率的重要因素。NEC目前被认为是新生儿期最常见的获得性胃肠道急症,并且这种疾病的结局普遍较差。为了制定最佳的预防和管理原则,需要进一步了解这种情况的病理生理学和发病机制。
Improvement in survival rates of low birth-weight infants particularly in the neonatal intensive care units of India appears to be accompanied by frequent recognition of Necrotizing enterocolitis (NEC) among early survivors. As the philosophy and practice of advanced care for tiny infants becomes more acceptable and affordable in the country, a steady increase in survival of such infants is predictable. However there is growing concern in India that NEC could become a significant contributor to morbidity and mortality in the future. NEC is currently regarded as the most common acquired gastrointestinal emergency in the newborn period, and the outcome of this disease is universally poor. Improved understanding of the pathophysiology and pathogenesis of this condition is required for formulating optimal principles of prevention and management.