PF155/RESA ANTIGEN IS LOCALIZED IN DENSE GRANULES OF PLASMODIUM-FALCIPARUM MEROZOITES
PF155/RESA ANTIGEN IS LOCALIZED IN DENSE GRANULES OF PLASMODIUM-FALCIPARUM MEROZOITES
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DOI：
10.1016/0014-4894(90)90037-d
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发表时间：
1990-10-01
影响因子：
2.1
通讯作者：
MILLER, LH
中科院分区：
文献类型：
--
作者：
AIKAWA, M;TORII, M;MILLER, LH
免疫电镜显示Pf155/RESA存在于恶性疟原虫的致密颗粒中，而不是先前认为的存在于微粒中。由于致密颗粒是在子体进入寄生液泡后释放出来的，因此Pf155/RESA在寄生虫入侵和后续发育过程中的作用可能与位于微元群中的分子不同。
Immunoelectron microscopy demonstrated the presence of Pf155/RESA in dense granules of Plasmodium falciparum merozoites rather than in micronemes as previously suggested. Since the dense granules are released after the merozoite enters the parasitophorous vacuole, the role of Pf155/RESA in invasion and subsequent steps of parasite development may differ from that of a molecule located in the micronemes.