Usefulness of eschar PCR for diagnosis of scrub typhus

Usefulness of eschar PCR for diagnosis of scrub typhus
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DOI:
10.1128/jcm.44.3.1169-1171.2006
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发表时间:
2006-03-01
影响因子:
9.4
通讯作者:
Shim, SK
Shim, SK
中科院分区:
医学2区
文献类型:
--
作者:
Lee, SH;Kim, DM;Shim, SK

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我们报告一位感染恙虫病的儿童,我们根据血清学及焦痂的聚合酶链反应作出诊断。患者接受阿奇霉素治疗,未发生任何并发症。在痂上进行巢式PCR可能既是恙虫病早期急性期的快速诊断试验,也是鉴别痂是否为恙虫病痂的鉴别试验。
We report here on the case of a child who was infected with scrub typhus, and we made the diagnosis according to the serology and by performing PCRs on the child's eschar. The patient was treated with azithromycin, and he did not experience any complications. Performing nested PCR on the eschar might be both a rapid diagnostic test for scrub typhus in the early acute stage and a differential test as to whether or not a scab is a scrub typhus eschar.