Relationship between age and measures of balance, strength and gait: linear and non-linear analyses
Relationship between age and measures of balance, strength and gait: linear and non-linear analyses
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DOI：
10.1042/cs20070301
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发表时间：
2008-06-01
期刊：
影响因子：
6
通讯作者：
Wark, John D.
中科院分区：
文献类型：
--
作者：
El Habert, Natalie;Erbas, Bircan;Wark, John D.
与年龄相关的平衡、步态和下肢肌肉力量指标的下降可能会导致跌倒和骨折的风险增加。先前的研究报告了这些指标可能与年龄相关的非线性下降，但方法论的选择限制了其解释。对 21-82 岁的健康社区居住女性 (n = 212) 进行力量 [Nicholas MMT（手动肌肉测试仪）]、步态 [CSA（临床步幅分析仪）]、活动 [HAP（人体活动概况）] 以及静态和动态平衡 [CBS（Chattecx 平衡系统）、LBT（洛德平衡测试）和 ST（步测试）] 的评估。为每个结果变量开发了 GAM（广义加性模型）来估计函数关系，其中年龄作为连续变量。表现可以维持到 45-55 岁，具体取决于结果测量。此后，随着年龄的增长，所有指标的表现都明显下降。总体而言，下肢力量测量 (MMT)、步态速度和双支撑持续时间 (CSA) 以及一些临床和实验室平衡测试 [ST LBT（睁眼）和 CBS] 与年龄存在显着的非线性关系。闭眼 LBT 和活动测量证明了线性关系。平衡能力、下肢肌肉力量和步态可能会随着年龄的增长而非线性下降。我们的研究表明，女性的年龄与平衡、肌肉力量和步态测量之间可能存在阈值效应。对这些阈值效应的进一步研究可能会对锻炼的最佳时机和其他干预措施产生影响，以降低跌倒和骨折的风险。
An age-related decline in balance, gait and lower-extremity muscle strength measures may lead to increased risk of falls and fractures. Previous studies have reported a possible non-linear age-related decline in these measures, but the choice of methodological approach has limited its interpretation. Healthy community-dwelling women (n = 212) 21-82 years of age were evaluated for strength [Nicholas MMT (manual muscle tester)], gait [CSA (clinical stride analyser)], activity [HAP (human activity profile)] and static and dynamic balance [CBS (Chattecx balance system), LBT (Lord's balance test) and the ST (step test)]. A GAM (generalized additive model) was developed for each outcome variable to estimate the functional relationship, with age as a continuous variable. Performance was maintained until 45-55 years of age, depending on the outcome measure. Thereafter a decline in performance was evident with increasing age in all measures. Overall, a significant nonlinear relationship with age was demonstrated for lower-extremity strength measures (MMT), velocity and double support duration of gait (CSA) and some clinical and laboratory balance tests [ST LBT (eyes open) and the CBS]. Linear relationships were demonstrated by the LBT with eyes closed and activity measures. Balance, lower-extremity muscle strength and gait may decline non-linearly with age. Our study suggests possible threshold effects between age and balance, muscle strength and gait measures in women. Further research into these threshold effects may have implications for the optimal timing of exercise and other interventions to reduce the risk of falls and fractures.