Monte Carlo simulation of Cherenkov imaging for Total Skin Electron Treatment with CT DICOM realistic patient geometry.
Monte Carlo simulation of Cherenkov imaging for Total Skin Electron Treatment with CT DICOM realistic patient geometry.
复制标题
使用 CT DICOM 真实患者几何形状进行全皮肤电子治疗切伦科夫成像的蒙特卡罗模拟。
DOI：
10.1117/12.2609027
复制
发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Zhu,TimothyC
中科院分区：
文献类型：
--
作者：
Zhong,Weili;Ong,Yihong;Miao,Tianshu;Pogue,BrianW;Zhu,TimothyC
该蒙特卡罗（MC）模拟研究提供了对患者剂量均匀性以及剂量和切伦科夫分布之间差异的评估，这在开发转换因子以将观察到的切伦科夫图像与TSET患者的实际剂量分布相关联方面非常宝贵。该MC模拟与TOPAS使用现实的患者几何形状与3D扫描仪在全皮肤电子治疗（TSET）在宾夕法尼亚大学。对于斯坦福大学技术中的每个治疗姿势，MC中产生的切伦科夫光子分布和剂量分布之间的差异与切伦科夫成像相机和患者皮肤上OSLD体内剂量测量之间观察到的差异一致。根据平板矩形PVC板的MC研究，切伦科夫和剂量之间的差异主要是由于扰流器。通过在无扰流器的PVC板上观察临床测量中的一致剂量和切伦科夫分布证实了这一点。通过将TSET治疗的6个姿势的MC输出一起投影到患者的有限元模型上，获得每名患者的累积剂量和切伦科夫分布。
This Monte Carlo (MC) simulation study provides an evaluation of dose uniformity in a patient and the difference between dose and Cherenkov distributions, which is invaluable in developing conversion factors to relate observed Cherenkov images to actual dose distributions for TSET patients. This MC simulations with TOPAS is performed using realistic patient geometries obtained with a 3D scanner during total skin electron treatments (TSET) at UPenn. For each treatment posture in the Stanford technique, the differences between Cherenkov photon distributions and dose distributions produced in MC are consistent with the differences observed between a Cherenkov imaging camera and in-vivo dose measurement with OSLD on patient skin. According to MC studies of a flat rectangular PVC board, the difference between Cherenkov and dose is mostly due to the spoiler. This is confirmed by observing consistent dose and Cherenkov distributions in clinical measurements on a PVC board without the spoiler. The accumulated dose and Cherenkov distributions for each patient are obtained by projecting the MC output of the 6 postures of the TSET treatment together onto a finite element model of the patient.