Intravenous coronary angiography: Experience in 276 patients
Intravenous coronary angiography: Experience in 276 patients
复制标题
静脉冠状动脉造影：276 例患者的经验
DOI：
10.1080/08940889808260850
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发表时间：
1998
影响因子：
--
通讯作者：
R. Ventura
中科院分区：
文献类型：
--
作者：
T. Dill;W. Dix;C. Hamm;M. Jung;W. Kupper;M. Lohmann;B. Reime;R. Ventura
冠状动脉造影术是冠心病患者公认的常规影像检查方法。近年来，这些手术的数量显著增加(1)。与这种侵入性方法相关的并发症很低，在1.5%的范围内，死亡率为0.1%(2)。由于手术的侵入性，进一步降低风险似乎很难实现。因此，利用非侵入性或微创性技术对冠状动脉进行成像已成为研究热点。传统的静脉数字减影血管造影术(DSA)采用时间减影方式，不适用于冠状动脉等快速运动的小血管，包括侧支血管。另一方面，双色摄影代表了一种基于能量减法的数字减法模式。同时获得了在33.17keV的对比剂(碘)的吸收K边缘(EK)正下方(EL)和之上(E，E)的两幅单色X射线图像，并对其进行了对数减去(图1)。在静脉注射后，只有同步辐射才能提供足够强度的单色X射线，以显示直径为1 mm、碘质量密度极低(1 mg/cm~2)的冠状动脉。在DESY的HASYLAB上，开发了用于二色摄影的线扫描系统Nikos。它由六个主要组成部分组成：a
Coronary angiography is the established routine imaging modality for patients with coronary artery disease. In recent years, the volume of these procedures has remarkably increased (1). Complications associated with this invasive approach are low-in the range of 1.5%-and the mortality is 0.1%(2). A further reduction of risk appears difficult to achieve because of the invasive nature of the procedure. Therefore, efforts have been made to image coronary arteries by non-invasive or minimal invasive techniques. Conventional intravenous digital subtraction angiography (DSA) uses a time subtraction mode and proved to be unsuitable for imaging of fastmoving small vessels like coronary arteries including sidebranches. Dichromography, on the other hand, represents a digital subtraction mode based on energy subtraction. Two images with monochromatic X-rays just below (El) and above (E,) the absorption K-edge (EK) of the contrast agent (iodine) at 33.17 keV are simultaneously obtained and logarithmically subtracted (Figure 1). Monochromatic X-rays of sufficient intensity to visualize coronary arteries of 1 mm in diameter with extremely low iodine mass density (1 mg/cm2) after intravenous injection are only provided by synchrotron radiation. At the HASYLAB at DESY, the line scan system NIKOS was developed for dichromography. It consists of six main components: a