Synthesis and preparation of novel 4-arm star-shape poly(carboxylic acid)s for improved light-cured glass-ionomer cements.
Synthesis and preparation of novel 4-arm star-shape poly(carboxylic acid)s for improved light-cured glass-ionomer cements.
复制标题
用于改进光固化玻璃离子水门汀的新型四臂星形聚（羧酸）的合成和制备。
DOI：
10.1016/j.dental.2006.02.008
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发表时间：
2007
期刊：
影响因子：
--
通讯作者：
Zhao,Jun
中科院分区：
文献类型：
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作者：
Xie,Dong;Park,Jong-Gu;Zhao,Jun
本研究的目的是合成和表征新型的四臂星形聚通过原子转移自由基聚合（ATRP）技术，将可光固化的甲基丙烯酸酯官能团原位连接到聚（AA）主链上，使用这些星形聚（AA）配制光固化玻璃离子水门汀（LCGIC），材料和方法使用ATRP合成4-臂聚（AA），并与甲基丙烯酸2-异氰酸乙酯（IEM）或甲基丙烯酸缩水甘油酯（GM）连接。聚合物用甲基丙烯酸2-羟乙酯（HEMA）或甲基丙烯酰基β-丙氨酸（MBA）、水、引发剂和Fuji II LC填料配制。抗压强度（CS）被用作评价所形成的骨水泥的工具。在测试之前，将样品在37 ℃的蒸馏水中调节24小时。与其线性对应物相比，4-臂聚（AA）显示出较低的粘度。IEM栓系和GM栓系的4臂聚（AA）构建的LCGIC均显示出显着高的机械强度。两种类型的共聚单体和接枝剂显着影响的机械强度。含MBA的聚（AA）骨水泥比含HEMA的骨水泥具有更高的CS。IEM栓系的聚（AA）骨水泥比GM栓系的骨水泥显示出更高的CS和Cement。结论本研究开发了一种新型的光固化四臂星形聚（AA）系统。与Fuji II LC相比，该系统在CS中为13%，在CSB中为178%，在FS中为123%。
OBJECTIVEThe objective of this study was to synthesize and characterize novel 4-arm star-shape poly(acrylic acid)s (poly(AA)s) via atom-transfer radical polymerization (ATRP) technique, tether in situ light-curable methacrylate functionalities onto the poly(AA) backbone, use these star-shape poly(AA)s to formulate the light-cured glass-ionomer cements (LCGICs), and evaluate the mechanical strengths of the formed cements.MATERIALS AND METHODSThe 4-arm poly(AA)s were synthesized using ATRP and tethered with either 2-isocyanatoethyl methacrylate (IEM) or glycidyl methacrylate (GM). The polymers were formulated with 2-hydroxyethyl methacrylte (HEMA) or methacryloyl beta-alanine (MBA), water, initiators, and Fuji II LC filler. Compressive strength (CS) was used as a tool to evaluate the formed cements. The specimens were conditioned in distilled water at 37°C for 24h prior to testing.RESULTSThe 4-arm poly(AA) showed a lower viscosity as compared to its linear counterpart. Both IEM-tethered and GM-tethered 4-arm poly(AA) constructed LCGICs showed significantly high mechanical strengths. Both types of co-monomer and grafting agent dramatically affected the mechanical strengths. The MBA-containing poly(AA) cements exhibited much higher CS than the HEMA-containing cements. The IEM-tethered poly(AA) cements showed much higher CS and DTS than the GM-tethered cements.CONCLUSIONSThis study developed a novel light-curable 4-arm star-shape poly(AA) system. The system was 13% in CS, 178% in DTS and 123% in FS, compared to Fuji II LC.