Parkinsonism in cerebrotendinous xanthomatosis.
Parkinsonism in cerebrotendinous xanthomatosis.
复制标题
脑腱黄瘤病中的帕金森病。
DOI：
10.2169/internalmedicine1962.30.189
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发表时间：
1991
期刊：
影响因子：
--
通讯作者：
M. Osame
中科院分区：
文献类型：
--
作者：
J. Fujiyama;M. Kuriyama;H. Yoshidome;M. Suehara;N. Eiraku;N. Kashio;M. Osame
本文报告一位以帕金森氏症为临床表现的腱性黄瘤病，包括面部油光、明显的运动不能、肌肉僵硬及静止性手震颤。脑磁共振成像（MRI）显示右侧苍白球和左侧壳核T2加权成像高信号区，T1加权成像略低信号区。还存在大脑皮质萎缩伴轻微脑室扩张和小脑萎缩。本文报告一例以帕金森综合征为表现的环磷酰胺中毒。帕金森综合征可能不是CTX的偶然表现，而是同一潜在素质的一种症状。
This report describes a case of cerebrotendinous xanthomatosis (CTX) accompanied by clinical manifestations of parkinsonism, including oily and masked face, marked akinesia, muscle rigidity and resting hand tremor. Magnetic resonance imaging (MRI) of the brain showed high intensity areas on T2 weighted imaging, and slightly low intensity areas on T1 weighted imaging in the right globus pallidus and the left putamen. Cerebral cortical atrophy with slight ventricular dilatation and cerebellar atrophy were present as well. This is a case report of CTX which manifested parkinsonism. Parkinsonism may not be a coincidental manifestation in CTX, but rather represent a symptom of the same underlying diathesis.