The randomized trials of breast cancer screening: what have we learned?

The randomized trials of breast cancer screening: what have we learned?
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DOI:
10.1016/j.rcl.2004.06.014
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发表时间:
2004-09-01
影响因子:
1.9
通讯作者:
Chen, THH
Chen, THH
中科院分区:
医学4区
文献类型:
--
作者:
Smith, RA;Duffy, SW;Chen, THH

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到目前为止,已经进行了8项乳房X线摄影筛查的随机对照试验。除了用实验设计评估筛查的有效性外,这些试验还为研究人员提供了在乳腺癌发展过程中比以前更早获得有关乳腺癌信息的机会。乳房X光检查试验提供了确凿的证据,证明提供检查的政策与乳腺癌死亡率的显著和实质性降低有关。
Eight randomized controlled trials of mammography screening have been conducted to date. In addition to evaluating the efficacy of screening with an experimental design, the trials provided investigators with access to information about breast cancers much earlier in their development than had previously been available. The trials of mammographic screening provide conclusive evidence that the policy of offering screening is associated with a significant and substantial reduction in breast cancer mortality.