HORSERADISH-PEROXIDASE INJECTION OF PHYSIOLOGICALLY CHARACTERIZED AFFERENT AND EFFERENT NEURONS IN THE GUINEA-PIG SPIRAL GANGLION

HORSERADISH-PEROXIDASE INJECTION OF PHYSIOLOGICALLY CHARACTERIZED AFFERENT AND EFFERENT NEURONS IN THE GUINEA-PIG SPIRAL GANGLION
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DOI:
10.1016/0378-5955(84)90042-x
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发表时间:
1984-01-01
期刊:
影响因子:
2.8
通讯作者:
ROBERTSON, D
ROBERTSON, D
中科院分区:
医学1区
文献类型:
--
作者:
ROBERTSON, D

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用辣根过氧化物酶注射豚鼠螺旋神经节的单个传入和传出神经元。它们可以在随后的组织学处理中被回收,并从神经节中的注射部位追踪到它们在Corti器官中的最终终止。所有反应性初级传入神经支配内毛细胞(58个神经元)。恢复了一条支配外毛细胞的外螺旋纤维。该细胞无尖峰信号,对声刺激无反应。具有先前归因于耳蜗传出神经的特性的神经元,终止于与其特征频率一致的耳蜗区域中的外毛细胞上。
Single afferent and efferent neurons in the guinea pig spiral ganglion were injected with horseradish peroxidase. They could be recovered in subsequent histological processing and traced from the injection site in the ganglion to their final termination in the organ of Corti. All responsive primary afferents innervated the inner hair cells (58 neurons). One outer spiral fiber innervating the outer hair cells was recovered. This cell was non-spiking and unresponsive to acoustic stimulation. Neurons having properties previously attributed to cochlear efferents, terminated on the outer hair cells in regions of the cochlea consistent with their characteristic frequencies.