THE EXERCISE TEST IN PERIODIC PARALYSIS

THE EXERCISE TEST IN PERIODIC PARALYSIS
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DOI:
10.1002/mus.880090805
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发表时间:
1986-10-01
期刊:
影响因子:
3.4
通讯作者:
DAUBE, JR
DAUBE, JR
中科院分区:
医学3区
文献类型:
--
作者:
MCMANIS, PG;LAMBERT, EH;DAUBE, JR

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在21例临床确诊的低钾、高钾或正常钾型周期性麻痹患者中,15例(71%)在2-5分钟的间歇性肌肉强自主收缩期间复合肌肉动作电位振幅增加大于正常。这种增加之后是幅度的逐步下降,幅度大于对照人群,并且在运动后的前20分钟内最快。振幅经常下降到低于运动前的水平。在9例继发于甲状腺毒症等疾病的周期性麻痹患者中,有6例出现了类似的反应。该试验可能对周期性麻痹患者的鉴别有价值。
Of 21 patients with clinically definite hypokalemic, hyperkalemic, or normokaelmic periodic paralysis, 15 (71%) had a greater than normal increase in compound muscle action potential amplitude during 2-5 minutes of intermittent strong voluntary contraction of the muscle. This increase was followed by a progressive decline in amplitude, which was greater than in a control population and which was most rapid during the first 20 minutes after exercise. The amplitude often decreased to a level below the preexercise level. A similar response was seen in six of nine patients with periodic paralysis secondary to disorders such as thyrotoxicosis. This test may have value in the identification of patients with periodic paralysis.