A convergent rhodium-catalysed asymmetric synthesis of tetrahydroquinolines.
A convergent rhodium-catalysed asymmetric synthesis of tetrahydroquinolines.
复制标题
DOI：
10.1039/c4cc04940c
复制
发表时间：
2014-08
影响因子：
4.9
通讯作者：
Ho Yin Li;J. Horn;A. Campbell;D. House;A. Nelson;S. Marsden
中科院分区：
文献类型：
--
作者：
Ho Yin Li;J. Horn;A. Campbell;D. House;A. Nelson;S. Marsden
Rh 催化的 2-氨基苯基硼酸衍生物的共轭加成被用于四氢喹啉的非对映选择性和不对称合成。在这两种情况下，四氢喹啉环系统的取代的组合变化是可能的。
Rh-catalysed conjugate additions of 2-aminophenyl boronic acid derivatives were exploited in diastereoselective and asymmetric syntheses of tetrahydroquinolines. In both cases, combinatorial variation of the substitution of the tetrahydroquinoline ring system was possible.