Uptake of HPV testing and extended cervical cancer screening intervals following cytology alone and Pap/HPV cotesting in women aged 30-65 years
Uptake of HPV testing and extended cervical cancer screening intervals following cytology alone and Pap/HPV cotesting in women aged 30-65 years
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DOI：
10.1007/s10552-017-0976-x
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发表时间：
2018-01-01
影响因子：
2.3
通讯作者：
Gravitt, Patti E.
中科院分区：
文献类型：
--
作者：
Silver, Michelle I.;Rositch, Anne F.;Gravitt, Patti E.
目的评估HPV检测的采用情况，并推荐在临床实践中延长宫颈癌筛查间隔，我们描述了每年接受Pap/HPV联合检测的情况，并根据患者特征估计了正常筛查之间的时间长度。2006年至2013年期间，来自约翰霍普金斯医院病理学数据系统的035名30-65岁女性。计算Cotest摄取率和仅cotest和细胞学检查的下一次筛选检查的中位时间。调整后的风险比估计使用考克斯比例风险模型，与随机效应调整聚类内clinic.ResultsCotest使用增加，
ObjectiveTo evaluate the adoption of HPV testing and recommended extended cervical cancer screening intervals in clinical practice, we described yearly uptake of Pap/HPV cotesting and estimated length of time between normal screens by patient characteristics.MethodsWe examined 55,575 Pap/HPV records from 27,035 women aged 30-65 years from the Johns Hopkins Hospital Pathology Data System between 2006 and 2013. Cotest uptake and median times to next screening test for cotests and cytology only were calculated. Adjusted hazard ratios were estimated using Cox proportional hazards models, with random effects adjustment for clustering within clinic.ResultsCotest usage increased from