Tuning of the excitability of transcortical cutaneous reflex pathways during mirror-like activity.
Tuning of the excitability of transcortical cutaneous reflex pathways during mirror-like activity.
复制标题
在类似镜子的活动期间调节经皮层皮肤反射通路的兴奋性。
DOI：
10.1007/s00221-011-2917-3
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发表时间：
2012
期刊：
影响因子：
2
通讯作者：
Ohtsuka H
中科院分区：
文献类型：
--
作者：
Ohtsuka H;Sasada S;Nakajima T;Futatsubashi G;Shimizu E;Komiyama T;Ohtsuka H
肌肉的自主收缩在对侧的同源肌肉中产生肌电图（EMG）活动（镜像活动），不仅在病理状态和婴儿中，而且在健康成人中。很少有研究探讨是否皮肤反射的反应时间任务的准备期间受到镜像活动。在本研究中，我们调查了9名健康受试者的皮肤反射的调制在左侧第一骨间肌（FDI），而他们进行了快速外展的右手食指在反应时间任务。通过对左手食指施加非伤害性电刺激来引起皮肤反射。我们发现，镜像活动发生在左FDI的EMG活动在右FDI大约开始。兴奋性E2组分在“Go”信号后约75 ms时选择性增加，这对应于镜像活性的开始。在“Go”信号后，抑制性I2（~90 ms）成分始终被调谐为兴奋。这些研究结果表明，长潜伏期反射，可能是经皮质的皮肤反射，微调有关的镜像活动。
Voluntary contraction of a muscle generates electromyographic (EMG) activity in the homologous muscle on the opposite side (mirror-like activity), not only in pathological states and in infants but also in healthy adults. Few studies have examined whether the cutaneous reflexes during the preparatory period of a reaction time task are affected by mirror-like activity. In the present study, we investigated the modulation of the cutaneous reflexes in the left first interosseous (FDI) muscle in 9 healthy subjects while they performed a quick abduction of the right index finger during a reaction time task. Cutaneous reflexes were elicited by applying non-noxious electrical stimulation to the left index finger. We found that mirror-like activity occurred in the left FDI at approximately the onset of EMG activity in the right FDI. The excitatory E2 component was selectively increased at ~75 ms after the “Go” signal, which corresponded to the onset of mirror-like activity. The inhibitory I2 (~90 ms) component was tuned consistently into excitation after the “Go” signal. These findings suggest that long latency reflexes, possibly transcortical cutaneous reflexes, are finely tuned in relation to mirror-like activity.