Left ventricular dysfunction in potential heart donors and its influence on recipient outcomes
Left ventricular dysfunction in potential heart donors and its influence on recipient outcomes
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DOI：
10.1016/j.jtcvs.2019.06.070
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发表时间：
2020-04-01
影响因子：
6
通讯作者：
Dellgren, Goran
中科院分区：
文献类型：
--
作者：
Oras, Jonatan;Doueh, Rana;Dellgren, Goran
目的：在器官供者中新发的左心功能不全是常见的，被认为是心脏利用的禁忌症。然而，这种功能障碍可能是由交感神经应激引起的，也可能是暂时的(Takotsubo综合征)。在这项研究中，我们评估了潜在心脏捐赠者左心功能障碍的发生率、模式和预测因素，并评估了其对受体结局的影响。方法：回顾2006年至2016年瑞典西部连续器官捐赠者的捐赠者记录。结果：在接受超声心动图评估的641名潜在心脏捐赠者中，左心功能不全(射血分数
Objectives: New onset of left ventricular (LV) dysfunction in organ donors is frequent and considered as a contraindication for utilization of the heart. However, such dysfunction might be caused by sympathetic stress and could be transient (Takotsubo syndrome). In this study, we assessed the incidence, pattern, and predictors of LV dysfunction in potential heart donors and evaluated its influence on recipient outcomes.Methods: Donor records of consecutive organ donors in western Sweden between 2006 and 2016 were reviewed. Recipients of transplanted donor hearts were identified in the Scandiatransplant database.Results: Of 641 potential heart donors who underwent echocardiographic assessment, LV dysfunction (ejection fraction