IR fiber-optic evanescent wave spectroscopy (FEWS) for sensing applications (Conference Presentation)
IR fiber-optic evanescent wave spectroscopy (FEWS) for sensing applications (Conference Presentation)
复制标题
用于传感应用的红外光纤倏逝波光谱 (FEWS)（会议演示）
DOI：
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发表时间：
2016
期刊：
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通讯作者：
A. Katzir
中科院分区：
文献类型：
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作者：
A. Katzir
我们开发了直径为 0.7-0.9 毫米的结晶 AgClBr 纤维，具有柔韧、无毒、不溶于水、透明度在 4-15 微米之间的特点。我们将这些光纤用于各种传感应用。中红外高灵敏度吸收测量可通过光纤倏逝波光谱 (FEWS) 进行。典型的 FEWS 系统基于三个中红外组件：可调谐光源、探测器和与样品接触的 AgClBr 光纤传感器。我们使用 FTIR 光谱仪或可调谐气体激光器或量子级联激光器 (QCL) 作为中红外源。我们使用该 FEWS 系统来测量气体、液体和固体。特别是我们将其用于多种生物医学应用。体内测量：（1）早期发现皮肤病（例如黑色素瘤）。 (2)细胞和细菌的测量。 (3) 角膜测量。体外测量：(4)尿路结石和胆道结石的表征。 (5) 血液测量。 FEWS方法简单、廉价并且不需要样品处理。它对于患者身体外部的诊断测量以及内窥镜测量非常有用。它对于测量从体内取出的组织样本也很有用。此外，我们还开发了扫描近场红外显微镜，用于中红外亚波长分辨率的光谱成像。各种 AgClBr 光纤传感器预计将成为未来医生手中的重要诊断工具。
We developed crystalline AgClBr fibers of diameters 0.7-0.9mm that are flexible, non-toxic, insoluble in water and highly transparent between 4-15µm. We used these fibers for various sensing applications. Highly sensitive absorption measurements in the mid-IR may be carried out by Fiber-optic Evanescent Wave Spectroscopy (FEWS). A typical FEWS system is based on three mid-IR components: a tunable source, a detector and a AgClBr fiber sensor that is brought in contact with the samples. We used FTIR spectrometers or tunable gas lasers or quantum cascade lasers (QCLs) as mid-IR sources. We used this FEWS system for measurements on gases, liquids and solids. In particular we used it for several biomedical applications. Measurements in vivo: (1) Early detection of skin diseases (e.g. melanoma). (2) Measurements on cells and bacteria. (3) Measurements on cornea. Measurements in vitro: (4) Characterization of urinary and biliary stones. (5) Blood measurements. The FEWS method is simple, inexpensive and does not require sample processing. It would be useful for diagnostic measurements on the outer part of the body of a patient, as well as for endoscopic measurements. It would also useful for measurements on tissue samples removed from the body. In addition we develop Scanning Near-field Infrared Microscope that will be used for spectral imaging with sub-wavelength resolution in the mid-IR. The various AgClBr fiber-optic sensors are expected to be important diagnostic tools at the hand of physicians in the future.