Cutoff Values of Brachial-Ankle Pulse Wave Velocity for Atherosclerotic Risks by Age and Sex in the Japanese General Population.

Cutoff Values of Brachial-Ankle Pulse Wave Velocity for Atherosclerotic Risks by Age and Sex in the Japanese General Population.
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DOI:
10.5551/jat.63557
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发表时间:
2023-05-01
影响因子:
4.4
通讯作者:
Ohishi M
Ohishi M
中科院分区:
医学2区
文献类型:
--
作者:
Mori R;Miyata M;Kubozono T;Inadome N;Kawasoe S;Ojima S;Kawabata T;Salim AA;Miyahara H;Tokushige K;Ohishi M

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目的:在本研究中,我们旨在分析臂踝脉搏波速度(baPWV)与Suita评分或Framingham风险评分之间的相关性,并根据日本大型年度健康检查数据中的这些评分评估,获得不同性别和年龄的baPWV心血管风险的截止值。 方法:本研究总共纳入了 25,602 名进行年度健康检查的参与者(14,539 名男性和 11,063 名女性)。使用受试者工作特征(ROC)曲线分析获得按性别和年龄分层的中危和高危人群的 baPWV 截止值。 结果:根据我们的研究结果,在两性中,Suita 评分与 baPWV 的相关性均优于 Framingham 风险评分(男性,Suita 评分 R2=0.41,Framingham 风险评分 R2=0.37;女性,Suita 评分 R2=0.54,Framingham 风险评分 R2=0.33)。 ROC曲线分析显示了使用Suita评分估计的中危和高危人群的baPWV截断值如下:男性中,40多岁的baPWV截断值为1,350 cm/s,50多岁的baPWV截断值为1,430 cm/s,60多岁的baPWV截断值为1,520 cm/s,70多岁的baPWV截断值为1,880 cm/s。在女性中,40 多岁的 baPWV 截止值为 1,350 cm/s,50 多岁的为 1,430 cm/s,60 多岁的为 1,570 cm/s,70 多岁的为 1,800 cm/s。 结论:我们证明,男性和女性的 baPWV 与 Suita 评分或 Framingham 风险评分显着相关,前者的相关性强于后者。我们提出了使用 Suita 评分估计的中危和高危人群 baPWV 的截断值。
Aim: In this study, we aim to analyze the correlation between brachial-ankle pulse wave velocity (baPWV) and Suita score or Framingham risk score and obtain the cutoff value of baPWV by sex and age for cardiovascular risk, as assessed by these scores in the large Japanese annual health checkup data. Methods: In total, 25,602 participants (14,539 men and 11,063 women), who had their annual health checkups, were included in this study. Cutoff values of baPWV for the moderate- and high-risk groups stratified by sex and age were obtained using a receiver operating characteristic (ROC) curve analysis. Results: As per our findings, the Suita score demonstrated better correlations with baPWV than the Framingham risk score in both sexes (men, Suita score R2=0.41 and Framingham risk score R2=0.37; women, Suita score R2=0.54 and Framingham risk score R2=0.33). The ROC curve analysis demonstrated the cutoff values of baPWV for moderate- and high-risk groups estimated using the Suita score, and they are as follows: in men, the baPWV cutoff values were 1,350 cm/s in the 40s, 1,430 cm/s in the 50s, 1,520 cm/s in the 60s, and 1,880 cm/s in the 70s. In women, the baPWV cutoff values were 1,350 cm/s in the 40s, 1,430 cm/s in the 50s, 1,570 cm/s in the 60s, and 1,800 cm/s in the 70s. Conclusions: We demonstrated that baPWV significantly correlated with the Suita score or Framingham risk score in both men and women, with the former presenting a stronger correlation than the latter. We propose the cutoff values of baPWV for moderate- and high-risk groups estimated using the Suita score.
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发表时间: 1998-05-12
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发表时间: 2010-12-09
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DOI: 10.1053/j.ajkd.2008.12.034
发表时间: 2009-06-01
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