Continuous subendothelial network formed by pericyte-like cells in human vascular bed
Continuous subendothelial network formed by pericyte-like cells in human vascular bed
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DOI：
10.1016/s0040-8166(98)80014-1
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发表时间：
1998-02-01
期刊：
影响因子：
2.6
通讯作者：
Orekhov, AN
中科院分区：
文献类型：
--
作者：
Andreeva, ER;Pugach, IM;Orekhov, AN
用抗周细胞抗体3G5对成人血管床周细胞样细胞的定位进行了免疫细胞化学研究。在大、中、小型动脉中，周细胞样细胞主要分布于血管的内膜下层、中膜外层和外膜中，在静脉中，周细胞分布于血管内膜的内下层、中膜和外膜中，在小动脉的内皮下层，软脑膜的小静脉和毛细血管。对不同大小血管内膜标本的观察表明，内皮下周细胞样细胞与其突起形成网络。因此，我们发现了一个连续的内皮下网络形成的周细胞样细胞在人血管床。
The localization of pericyte-like cells in adult human vascular bed was studied immunocytochemically using anti-pericyte antibody - 3G5. In large-, medium-and small-size arteries, pericyte-like cells were identified in the inner intimal layer, predominantly in the subendothelium, in the outer layer of the media and in the adventitia in vasa vasora, In veins, pericytes were found in the subendothelial layer of the intima, in the media and in the adventitia where they were located in vasa vasora, These cells were revealed in the subendothelium of arterioles, venules and capillaries of the pia mater encephali. Examination of intimal en face preparations of various size blood vessels showed that subendothelial pericyte-like cells form a network contacting with their processes. Thus we found a continuous subendothelial network formed by pericyte-like cells in the human vascular bed.