Effect of Electrode to Modiolus Distance on Electrophysiological and Psychophysical Parameters in CI Patients With Perimodiolar and Lateral Electrode Arrays
Effect of Electrode to Modiolus Distance on Electrophysiological and Psychophysical Parameters in CI Patients With Perimodiolar and Lateral Electrode Arrays
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DOI：
10.1097/mao.0000000000002751
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发表时间：
2020-10-01
影响因子：
2.1
通讯作者：
Lenarz, Thomas
中科院分区：
文献类型：
--
作者：
Degen, Chantal Vanessa;Buechner, Andreas;Lenarz, Thomas
目的：旨在研究最新的皮质核532电极阵列与直型Nucleus 522和弯型512阵列相比的颅内位置，并确定电极-蜗轴距离对电诱发复合动作电位、C水平、电诱发镫骨肌反射阈值（ESRT）和阻抗的影响。研究方法：使用Comet（髋关节测量工具）程序评价了30例植入了髋关节髓核532、522和512植入体的患者的术后高分辨率锥形束计算机断层扫描图像，以确定22个单独电极触点与内侧壁之间的距离。术中记录ESRT，并在多个时间点测量电生理和心理物理参数，包括初始激活后的第一次拟合。结果如下：在perimodiolar阵列中的电极-蜗轴距离在整个阵列上均匀地小，而在直电极载体中，其沿阵列的长度沿着显著变化。电诱发的复合动作电位阈值和C-水平随着到蜗轴的距离的增加而增大。阵列之间的阻抗和镫骨肌反射阈值没有显著差异。我们的研究结果表明，电极位置对电生理和心理物理参数都有显着影响，而阻抗和ESRT不受影响。结论：新的工具可以用于高分辨率锥形束计算机断层扫描图像的评价，以确定人工耳蜗植入后的个体电极-蜗轴距离。本研究的结果表明，电极-蜗轴距离和电生理和心理物理参数之间的相关性不足以根据成像数据调整CI拟合。
Objectives: To investigate the intracochlear position of the latest Cochlear Nucleus 532 electrode array compared with the straight Nucleus 522 and the precurved 512 arrays and determine the effect of the electrode-modiolus distance on electrically evoked compound action potential, C-levels, electrically evoked stapedius reflex thresholds (ESRTs), and impedances. Methods: Postoperative high-resolution cone beam computational tomography images of 30 patients with Cochlear Nucleus 532, 522, and 512 implants were evaluated using the Comet (Cochlea Measurement Tool) program to determine the distance between the 22 individual electrode contacts and the medial wall. ESRTs were documented intraoperatively and electrophysiological as well as psychophysical parameters were measured at multiple time points including the first fitting after the initial activation. Results: The electrode-modiolus distance in perimodiolar arrays is uniformly small across the array, whereas in a straight electrode carrier it varies significantly along the length of the array. Electrically evoked compound action potential thresholds and C-levels are larger with increased distance to the modiolus. Impedances and stapedius reflex thresholds do not differ significantly between the arrays. Our results show that the electrode position has a significant effect on both electrophysiological and psychophysical parameters, while impedances and ESRTs are not impacted. Conclusion: Novel tools can be used in the evaluation of high resolution cone beam computational tomography images to determine individual electrode-modiolus distances after cochlear implantation. The results of this study suggest that the correlations between electrode-modiolus distance and electrophysiological and psychophysical parameters are not sufficiently strong to adjust CI-fitting based on imaging data.