Synthesis of Benzyltributylstannanes by the Reaction of N-Tosylhydrazones with Bu3SnH
Synthesis of Benzyltributylstannanes by the Reaction of N-Tosylhydrazones with Bu3SnH
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N-甲苯磺酰腙与Bu3SnH反应合成苄基三丁基锡
DOI：
10.1021/acs.joc.6b02639
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发表时间：
2017-01-06
影响因子：
3.6
通讯作者：
Wang, Jianbo
中科院分区：
文献类型：
--
作者：
Qiu, Di;Wang, Shuai;Wang, Jianbo
开发了一种有效的甲锡烷基化方法，可直接与羰基化合物反应或与对甲苯磺酰腙反应。在不含过渡金属的条件下，合成了一系列苄基和烷基三丁基锡烷。在不纯化苄基三丁基锡烷中间体的情况下，进行了包括锡烷基化/Stille交叉偶联反应的串联转化，得到一系列二芳基甲烷衍生物。
An efficient stannylation process with Ntosylhydrazones or directly with carbonyl compounds has been developed. A series of functionalized benzyl-and alkyltributylstannanes can be synthesized in moderate to good yields under transition-metal-free conditions. Tandem transformations involving stannylation/Stille cross-coupling reaction have been carried out without purification of the benzyltributylstannane intermediates to afford a series of diarylmethane derivatives.