Surgical results of internal limiting membrane flap inversion and internal limiting membrane peeling for macular hole.
Surgical results of internal limiting membrane flap inversion and internal limiting membrane peeling for macular hole.
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DOI：
10.1371/journal.pone.0203789
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Nakazawa T
中科院分区：
文献类型：
--
作者：
Ota H;Kunikata H;Aizawa N;Nakazawa T
内界膜（ILM）是视网膜的正常部分，并且ILM去除的结果尚未得到充分研究。ILM皮瓣翻转是最近发展的一种技术，可提高黄斑裂孔（MH）手术的成功率。因此，我们比较了接受微切口玻璃体切除术（MIVS）联合ILM瓣翻转或传统ILM剥离治疗MH的患者的解剖学闭合率和视力结果。方法回顾性分析90眼MH的临床资料。根据MIVS手术方法将患者分为两组（第1组：ILM瓣翻转，46只眼;第2组：ILM剥离，44只眼）。两组的术前特征相似，两组之间术后1个月或6个月VA无显著差异（分别为P = 0.25和P = 0.42）。然而，第1组的手术成功率显著高于第2组（P = 0.04;分别为46/46：100%和41/44：93%）。多元回归分析显示，在第2组中，眼轴长度和MH直径是预测术后6个月BCVA的独立因素（分别为P = 0.001和P = 0.03），而在第1组中，MH直径是预测术后6个月VA的独立因素（P = 0.03）。Logistic回归分析显示，眼轴长度（OR = 2.11; P = 0.02;曲线下面积：0.94;截断评分：28.4 mm）是第2组手术失败的独立因素。我们的研究结果表明，MIVS与ILM皮瓣翻转可能是最适合治疗MH，特别是在高度近视患者。
The internal limiting membrane (ILM) is a normal part of the retina, and the outcomes of ILM removal have not been fully investigated. ILM flap inversion is a recently developed technique that increases the success rate of macular hole (MH) surgery. Thus, we compared the anatomical closure rate and visual outcome in patients undergoing microincision vitrectomy surgery (MIVS) with ILM flap inversion or conventional ILM peeling for the treatment of MH. The medical records of 90 eyes with MH were reviewed retrospectively. The patients were classified into two groups based on MIVS procedure (group 1: ILM flap inversion, 46 eyes; group 2: ILM peeling, 44 eyes). Preoperative characteristics were similar in the two groups, and there were no significant differences in 1 month- or 6 month-postoperative VA between the groups (P = 0.25 and P = 0.42, respectively). However, the surgical success rate was significantly higher in group 1 than group 2 (P = 0.04; 46/46: 100% and 41/44: 93%, respectively). Multiple regression analysis revealed that axial length and MH diameter were independent factors predicting 6-month postoperative BCVA in group 2 (P = 0.001 and P = 0.03, respectively), and that MH diameter was an independent factor predicting 6-month postoperative VA in group 1 (P = 0.03). Logistic regression analysis revealed that axial length (OR = 2.11; P = 0.02; area under the curve: 0.94; cut off score: 28.4 mm) was an independent factor indicating surgical failure in group 2. Our results suggest that MIVS with ILM flap inversion might be best suited to treat MH, particularly in patients with high myopia.
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影响因子：
4.2
作者：
Kuriyama, Shoji;Hayashi, Hisako;Matsumoto, Miho
通讯作者：
Matsumoto, Miho
影响因子：
--
作者：
Michalewska, Z.;Michalewski, J.;Nawrocki, J.
通讯作者：
Nawrocki, J.
影响因子：
4.2
作者：
Kimura, H;Kuroda, S;Nagata, M
通讯作者：
Nagata, M
DOI：
10.1097/iae.0000000000001010
发表时间：
2016-09-01
影响因子：
3.3
作者：
Olenik, Andrea;Rios, Jose;Mateo, Carlos
通讯作者：
Mateo, Carlos
影响因子：
13.7
作者：
Michalewska, Zofia;Michalewski, Janusz;Nawrocki, Jerzy
通讯作者：
Nawrocki, Jerzy