Depressive symptoms and cardiovascular health by the American Heart Association's definition in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study.

Depressive symptoms and cardiovascular health by the American Heart Association's definition in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study.
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DOI:
10.1371/journal.pone.0052771
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发表时间:
2012
期刊:
影响因子:
3.7
通讯作者:
Safford MM
Safford MM
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Kronish IM;Carson AP;Davidson KW;Muntner P;Safford MM

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抑郁症状与心血管事件的发生和复发增加相关。2010年,美国心脏协会发布了Life's Simple 7,这是一个评估心血管健康的指标,通过4种健康行为(吸烟,体育活动,体重指数,饮食)和3种生物指标(胆固醇,血压,葡萄糖)来衡量。抑郁症状和生活简单7之间的联系尚未被探索。这些分析使用了20,093名年龄≥45岁的参与者的数据,这些参与者在2003年至2007年期间入组了卒中的地理和种族差异原因(REGARDS)研究,并且具有完整的Life's Simple 7组分数据。在有和没有抑郁症状的参与者之间,比较了每个生活简单7分和生活简单7分的理想,中等和不良健康状况的患病率。抑郁症状采用4项抑郁症流行病学研究中心量表测量。有抑郁症状的参与者更有可能在生活简单7个组成部分中的每一个上都有差的水平,而不是胆固醇[校正的患病率比(95%CI):吸烟1.41(1.29-1.55);体力活动1.38(1.31-1.46);体重指数1.09(1.04-1.15);饮食1.08(1.06-1.10);血压1.11(1.02-1.21);葡萄糖1.24(1.09-1.41)]。抑郁症状增加与Life's Simple 7总分较低之间存在分级相关性。抑郁症状与总体生活简单7和代表健康行为和生物因素的个体组成部分的心血管健康状况较差相关。
Depressive symptoms are associated with increased incident and recurrent cardiovascular events. In 2010, the American Heart Association published the Life’s Simple 7, a metric for assessing cardiovascular health as measured by 4 health behaviors (smoking, physical activity, body mass index, diet) and 3 biological measures (cholesterol, blood pressure, glucose). The association between depressive symptoms and the Life’s Simple 7 has not yet been explored. Data from 20,093 participants ≥45 years of age who enrolled in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study between 2003 and 2007 and who had complete data available on Life’s Simple 7 components were used for these analyses. The prevalence of ideal, intermediate, and poor health on each Life’s Simple 7 component and total Life’s Simple 7 scores were compared between participants with and without depressive symptoms. Depressive symptoms were measured using the 4-item Centers for Epidemiologic Studies of Depression scale. Participants with depressive symptoms were more likely to have poor levels on each of the Life’s Simple 7 components other than cholesterol [adjusted prevalence ratios (95% CI): smoking 1.41 (1.29–1.55); physical activity 1.38 (1.31–1.46); body mass index 1.09 (1.04–1.15); diet 1.08 (1.06–1.10); blood pressure 1.11 (1.02–1.21); glucose 1.24 (1.09–1.41)]. There was a graded association between increasing depressive symptoms and lower total Life’s Simple 7 score. Depressive symptoms are associated with worse cardiovascular health on the overall Life’s Simple 7 and on individual components representing both health behaviors and biological factors.
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