Preparation of monodisperse multiple emulsions at high production rates by multi-stage premix membrane emulsification
Preparation of monodisperse multiple emulsions at high production rates by multi-stage premix membrane emulsification
复制标题
DOI：
10.1016/j.memsci.2004.07.008
复制
发表时间：
2004-11
影响因子：
9.5
通讯作者：
G. Vladisavljević;M. Shimizu;T. Nakashima
中科院分区：
文献类型：
--
作者：
G. Vladisavljević;M. Shimizu;T. Nakashima
采用平均孔径为10.7μm的shirasu多孔玻璃（SPG）膜，采用多级（重复）预混膜乳化法制备了W/O/W乳液。在20-300kPa的恒压差条件下，对平均粒径约为100μm的含液滴的粗乳状液进行5-6次均质，进一步实现液滴的均质化和粒径缩小。粒径均匀性的最佳条件是在压力差为100kPa的条件下进行3次均质循环，在此条件下，外W/O颗粒平均粒径为9μm，粒径分布跨度低至0.28。单段工艺的最佳压差较大，但在较小压力下制备的乳液粒径分布比多段工艺更宽。跨膜通量在1.8 ~ 37m3m−2h−1之间，随压差的增大和W/O颗粒含量的降低而增大。在1-60vol. %的浓度范围内，每个循环中W/O颗粒的平均大小显著恒定。
Multiple W/O/W emulsions have been prepared by multi-stage (repeated) premix membrane emulsification using Shirasu-porous glass (SPG) membrane with a mean pore size of 10.7μm. A coarse emulsion containing droplets with a mean particle size of about 100μm was homogenized 5–6 times through the same membrane at a constant pressure difference of 20–300kPa to achieve additional droplet homogenization and size reduction. The optimum conditions with regard to particle size uniformity were three homogenization cycles at a pressure difference of 100kPa, under which the mean size of outer W/O particles was 9μm and the span of particle size distribution was as low as 0.28. The optimum pressure difference in a single-stage process was higher, but the particle size distribution of prepared emulsions was broader than in a multi-stage process at smaller pressures. The transmembrane flux was in the range of 1.8–37m3m−2h−1and increased with increasing pressure difference and decreasing the content of W/O particles. The mean size of W/O particles in each cycle was remarkably constant over a wide range of their concentration of 1–60vol.%.