Cycling Induced by Electrical Stimulation Improves Muscle Activation and Symmetry During Pedaling in Hemiparetic Patients
Cycling Induced by Electrical Stimulation Improves Muscle Activation and Symmetry During Pedaling in Hemiparetic Patients
复制标题
DOI：
10.1109/tnsre.2012.2191574
复制
发表时间：
2012-05-01
影响因子：
4.9
通讯作者：
Pedrocchi, Alessandra
中科院分区：
文献类型：
--
作者：
Ambrosini, Emilia;Ferrante, Simona;Pedrocchi, Alessandra
一项随机对照试验，涉及35名急性偏瘫后患者，证明了功能性电刺激（FES-循环）诱导的为期四周的循环治疗促进运动恢复。通过分析该研究期间获得的额外数据，本研究调查了这些改善是否与肌肉力量和运动协调的变化有关。参与者被随机分配接受FES循环或安慰剂FES循环。临床结局指标为：运动指数（MI）、步态速度、股直肌和股二头肌的肌电图激活，以及在随意踩踏期间每条腿产生的机械功。为了与正常值进行比较，健康成年人也进行了踩踏板测试。患者在培训前、培训后和随访时进行评估。在MI评分和机械工作不平衡方面，发现FES治疗患者的显著治疗效果，而步态速度差异不显著（ANCOVA）。在FES组中，轻瘫肌肉的激活显著改善，而在安慰剂组中没有发现显著变化（Friedman检验）。我们的研究结果表明，FES自行车训练引起的运动功能的改善与双腿的对称参与和运动协调性的改善有关。
A randomized controlled trial, involving 35 post-acute hemiparetic patients, demonstrated that a four-week treatment of cycling induced by functional electrical stimulation (FES-cycling) promotes motor recovery. Analyzing additional data acquired during that study, the present work investigated whether these improvements were associated to changes in muscle strength and motor coordination. Participants were randomized to receive FES-cycling or placebo FES-cycling. Clinical outcome measures were: the Motricity Index (MI), the gait speed, the electromyography activation of the rectus femoris and biceps femoris, and the mechanical work produced by each leg during voluntary pedaling. To provide a comparison with normal values, healthy adults also carried out the pedaling test. Patients were evaluated before, after training, and at follow-up visits. A significant treatment effect in favor of FES-treated patients was found in terms of MI scores and unbalance in mechanical works, while differences in gait speed were not significant (ANCOVA). Significant improvements in the activation of the paretic muscles were highlighted in the FES group, while no significant change was found in the placebo group (Friedman test). Our findings suggested that improvements in motor functions induced by FES-cycling training were associated with a more symmetrical involvement of the two legs and an improved motor coordination.