On the trabecular "thickness" - Number problem
On the trabecular "thickness" - Number problem
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DOI：
10.1359/jbmr.1999.14.11.1816
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发表时间：
1999-11-01
影响因子：
6.2
通讯作者：
Frost, HM
中科院分区：
文献类型：
--
作者：
Frost, HM
随着年龄的增长和骨质疏松症中骨小梁数量的减少似乎是自然不可逆的。一种观点认为，骨强度的损失也是不可逆的，但另一种观点认为，剩余的骨小梁可以增加其强度，主要是通过增厚。这种情况是否会发生，对于骨质疏松症的研究和管理以及一些生物力学问题都很重要。这篇文章回顾了有关这一问题的证据和想法。这说明了为什么第二种观点可能是正确的，尽管以前的研究没有发现这一点，但这种观点仍然需要得到一般骨骼科学界能够接受的证据。
The decrease in trabecular number with aging and in osteoporosis seems to be naturally irreversible. In one view the resulting loss of bone strength mould be irreversible too, but in another view the remaining trabeculae could increase their strength, chiefly by thickening. Whether that can occur has become important for osteoporosis research and management as well as for some biomechanical issues. This article reviews evidence and ideas that concern that matter. It suggests why the second view could be correct although previous studies did not detect it. However, that view still needs the kind of proof the general skeletal science community could accept.