Prevalence of co-morbid depression in out-patients with type 2 diabetes mellitus in Bangladesh.
Prevalence of co-morbid depression in out-patients with type 2 diabetes mellitus in Bangladesh.
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DOI：
10.1186/1471-244x-12-123
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发表时间：
2012-08-22
期刊：
影响因子：
4.4
通讯作者：
Rahman M
中科院分区：
文献类型：
--
作者：
Roy T;Lloyd CE;Parvin M;Mohiuddin KG;Rahman M
人们对孟加拉国糖尿病患者中抑郁症的患病率知之甚少。这项研究调查了孟加拉国门诊2型糖尿病患者的患病率和与抑郁相关的因素。在这项横断面研究中，来自孟加拉国三家糖尿病诊所的483名糖尿病门诊患者被邀请参加。其中417名患者参加了试验。抑郁症状是使用先前开发的和文化标准化的世界卫生组织-5幸福感指数(WHO-5)和患者健康问卷-9(PHQ-9)的孟加拉和西尔赫蒂版本进行衡量的，并具有预先定义的截止分数。数据是通过两种不同的方式收集的；例如，标准辅助收集和音频问卷方法。通过回归分析探讨抑郁与患者特征之间的关系。采用语音问卷调查法，抑郁症状发生率分别为34%(PHQ-9评分 ≥ 5)和36%( <； 52)。无论问卷的类型(PHQ-9 vs.WHO-5)、语言(Sylheti vs.Bengali)和分娩方法(标准辅助方法vs.音频方法)，患病率都是相似的。使用PHQ-9或WHO-5问卷调查抑郁症状的显著预测因素是：年龄、收入、性别、治疗强度和合并心血管疾病。此外，抑郁与血糖控制不良和许多共病情况密切相关。这项研究表明，抑郁症在孟加拉的门诊2型糖尿病患者中很常见。在识别、筛查和治疗水平仍然较低的情况下，卫生保健提供者需要将重点放在诊断、转诊和有效治疗这一重要疾病上，以改善服务提供。
Little is known about the prevalence of depression in people with diabetes in Bangladesh. This study examined the prevalence and factors associated with depression in out-patients with Type 2 diabetes in Bangladesh. In this cross-sectional study a random sample of 483 diabetes out-patients from three diabetes clinics in Bangladesh was invited to participate. Of them 417 patients took part. Depressive symptoms were measured using previously developed and culturally standardized Bengali and Sylheti versions of the World HealthOrganization-5 Well Being Index (WHO-5) and the Patient Health Questionairre-9 (PHQ-9) with predefined cut-off scores. Data was collected using two different modes; e.g. standard assisted collection and audio questionnaire methods. Associations between depression and patient characteristics were explored using regression analysis. The prevalence of depressive symptoms was 34% (PHQ-9 score ≥ 5) and 36% (WHO-5 score < 52) with audio questionnaire delivery method. The prevalence rates were similar regardless of the type (PHQ-9 vs. WHO-5) and language (Sylheti vs. Bengali) of the questionnaires, and methods of delivery (standard assisted vs. audio methods). The significant predictors of depressive symptoms using either the PHQ-9 or WHO-5 questionnaires were; age, income, gender, treatment intensity, and co-morbid cardiovascular disease. Further, depression was strongly associated with poor glycaemic control and number of co-morbid conditions. This study demonstrated that depression prevalence is common in out-patients with type 2 diabetes in Bangladesh. In a setting where recognition, screening and treatment levels remain low, health care providers need to focus their efforts on diagnosing, referring and effectively treating this important disease in order to improve service delivery.