Hyperthyroidism and Other Causes of Thyrotoxicosis: Management Guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists
Hyperthyroidism and Other Causes of Thyrotoxicosis: Management Guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists
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DOI：
10.1089/thy.2010.0417
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发表时间：
2011-06-01
期刊：
影响因子：
6.6
通讯作者：
Stan, Marius N.
中科院分区：
文献类型：
--
作者：
Bahn, Rebecca S.;Burch, Henry B.;Stan, Marius N.
背景：甲状腺毒症有多种病因，表现和潜在的治疗。适当的治疗需要准确的诊断，并受共存的医疗条件和患者的偏好。本文介绍了以证据为基础的临床指南甲状腺毒症的管理，这将是有用的全科医生和亚专科医生和其他人提供照顾病人这种conditions.Methods：这些指南的发展委托美国甲状腺协会与美国临床内分泌学家协会。美国甲状腺协会和美国临床内分泌学家协会组建了一个由临床专家组成的工作组，撰写了这份报告。工作组使用系统性PubMed检索并辅以其他已发表材料检查了相关文献。采用循证医学方法，结合专家组的知识和经验，制定了文本和一系列具体建议。强度的建议和质量的证据支持每一个被评为根据建议的分级，评估，开发和评价Group.Results：临床主题包括初步评价和管理的甲状腺毒症;管理Graves'甲亢使用放射性碘，抗甲状腺药物，或手术;使用放射性碘或手术治疗毒性多结节性甲状腺肿或毒性腺瘤;儿童、青少年或妊娠患者的Graves病;亚临床甲状腺功能亢进症; Graves眼病患者的甲状腺功能亢进症;以及其他甲状腺毒症病因的治疗。100个循证建议被开发，以帮助甲状腺毒症患者的护理，并分享工作组认为是当前，合理和最佳的医疗实践。
Background: Thyrotoxicosis has multiple etiologies, manifestations, and potential therapies. Appropriate treatment requires an accurate diagnosis and is influenced by coexisting medical conditions and patient preference. This article describes evidence-based clinical guidelines for the management of thyrotoxicosis that would be useful to generalist and subspeciality physicians and others providing care for patients with this condition.Methods: The development of these guidelines was commissioned by the American Thyroid Association in association with the American Association of Clinical Endocrinologists. The American Thyroid Association and American Association of Clinical Endocrinologists assembled a task force of expert clinicians who authored this report. The task force examined relevant literature using a systematic PubMed search supplemented with additional published materials. An evidence-based medicine approach that incorporated the knowledge and experience of the panel was used to develop the text and a series of specific recommendations. The strength of the recommendations and the quality of evidence supporting each was rated according to the approach recommended by the Grading of Recommendations, Assessment, Development, and Evaluation Group.Results: Clinical topics addressed include the initial evaluation and management of thyrotoxicosis; management of Graves' hyperthyroidism using radioactive iodine, antithyroid drugs, or surgery; management of toxic multinodular goiter or toxic adenoma using radioactive iodine or surgery; Graves' disease in children, adolescents, or pregnant patients; subclinical hyperthyroidism; hyperthyroidism in patients with Graves' ophthalmopathy; and management of other miscellaneous causes of thyrotoxicosis.Conclusions: One hundred evidence-based recommendations were developed to aid in the care of patients with thyrotoxicosis and to share what the task force believes is current, rational, and optimal medical practice.